Immune checkpoint inhibitors, including Bristol-Myers Squibb’s Opdivo, Merck & Co.’s Keytruda, and Roche’s Tecentriq, are revolutionizing the therapeutic strategies for several cancers. This report focuses on: malignant melanoma, primarily the adjuvant setting, which has been newly penetrated by the immune checkpoint inhibitors; bladder cancer, for which reimbursement of the drug class under study is not proving to be straightforward; and, squamous cell carcinoma of the head and neck (SCCHN), an indication with few labeled treatments and high unmet need. As novel immune checkpoint inhibitor therapies prepare to enter the markets under study, and label expansions for existing treatments loom large on the horizon, optimal market access opportunities beckon in France, Germany, Italy, Spain, and the UK, but payer-imposed reimbursement restrictions and cost-containment strategies will increasingly play a pivotal role in shaping medical oncologists’ prescribing practices for these high-cost therapies, and manufacturers must be prepared to compromise in order to maximize return on investment.
European Access & Reimbursement provides integrated brand-level and country-specific analysis of primary market research conducted with payers and prescribers to examine reimbursement dynamics and evaluate the impact of payer policy on prescribing behavior.
France, Germany, Italy, Spain, and United Kingdom
KEY DRUGS COVERED
Keytruda, Opdivo, Tecentriq, Yervoy, spartalizumab, Imfinzi, tremelimumab, Bavencio