Diabetic macular edema (DME) is caused by diabetes and is characterized by leaking fluid from abnormal blood vessels in the eye; this fluid can lead to swelling of the macula and visual impairment. Intravitreal vascular endothelial growth factor (VEGF) inhibitors, such as Regeneron / Bayer’s Eylea, Roche / Novartis’s Lucentis, and Roche’s Avastin, are the most common pharmacotherapies for treating DME, owing to their proven efficacy and safety. AbbVie’s Ozurdex and Alimera Sciences’ Iluvien, two long-acting corticosteroid implants, are also used to treat DME. However, these drugs all have clinical shortcomings in terms of efficacy, safety, and/or delivery, creating opportunities for new and improved alternatives. Our content examines the key treatment drivers and analyzes the greatest areas of unmet need, thereby presenting the opportunities in this space.
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PRODUCT DESCRIPTION
Unmet Need provides quantitative insight into U.S. and European physician perceptions of key treatment drivers and goals and the current level of unmet need for a specific disease. Commercial opportunities are analyzed, and the extent to which emerging therapies may capitalize on these opportunities is evaluated.
Markets covered: United States, United Kingdom, France, Germany
Primary research: Survey of 60 U.S. and 30 European ophthalmologists fielded in March 2022
Key companies: Roche, Regeneron, Novartis, Bayer, AbbVie, Alimera Sciences
Key drugs: Eylea, Lucentis, Avastin, Ozurdex, Iluvien