Chronic kidney disease (CKD) is caused by structural or functional abnormalities in the kidney that impair its ability to filter blood. The CKD drug market primarily comprises antihypertensive agents and SGLT-2 inhibitors, which are intended to delay disease progression. RAAS inhibitors are the standard-of-care therapy for CKD. SGLT-2 inhibitors are emerging to become another standard-of-care therapy for CKD treatment. In 2021 and 2023, AstraZeneca’s Farxiga and Eli Lilly’s Jardiance, respectively, received FDA approval for treatment of CKD regardless of diabetes status. Johnson & Johnson’s Invokana is approved for treatment of diabetic kidney disease, a major subpopulation of CKD patients. In 2021, Bayer’s Kerendia, a novel nonsteroidal selective mineralocorticoid receptor antagonist (MRA), was approved for treatment of diabetic kidney disease patients after it demonstrated significant cardioprotective and renoprotective benefits in the FIDELIO-DKD and FIGARO-DKD trials. This report provides insights on how the key drug classes for CKD treatment are used in newly diagnosed and recently treated CKD patients
Questions answered
Markets covered: United States
Key companies: AstraZeneca, Eli Lilly, Boehringer Ingelheim
Key drugs: Jardiance, Farxiga, Invokana, Kerendia
Product description
Treatment Algorithms: Claims Data Analysis provides detailed, quantitative analysis of the treatment journey and brand usage across lines of therapy and overall using real-world, patient-level claims data so that marketers can accurately assess their source of business, benchmark usage against competitors, and quantify areas of opportunity for their marketed or emerging brand.
Key feature
Dashboard featuring interactive visuals, easy navigation, and expanded analyses