Eisai / Biogen’s Leqembi (lecanemab) gained accelerated and full FDA approval in 2023 based on positive clinical and biomarker outcomes from the Phase 3 CLARITY-AD trial. With the U.S. CMS covering the drug in line with its label and broadening reimbursement of PET scans used to establish diagnoses and determine treatment eligibility, Leqembi is poised to capitalize on the unfulfilled potential for an AD DMT. However, logistic hurdles on the path to diagnosis and treatment initiation must be overcome to unlock the full potential of a DMT in the AD market. This survey-based report assesses awareness, perceptions, and usage of the drug among U.S. neurologists and geriatricians who manage patients with early AD as well as unspecified dementia or unspecified mild cognitive impairment. With additional DMTs poised to reach the market in 2024, the data will provide insight into drivers and constraints on the use of Leqembi and similar agents and will highlight opportunities to support current and future prescribers to drive uptake.
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Clarivate’s Special Topics reports use quantitative and/or qualitative primary research to assess evolving trends and market effects in dynamic disease areas. Insights from this report will help gauge competitors in shaping their market strategies, identifying potential areas for differentiation, and physician’s receptivity.