Hidradenitis Suppurativa – Executive Insights – Executive Insights (US)


Hidradenitis suppurativa (HS) is a chronic relapsing inflammatory disorder affecting hair follicles. Humira is the only FDA-approved therapy for the disease; its use is limited—based on the label—to patients with moderate to severe disease. In addition, a variety of therapies (e.g., antibiotics, hormonal agents, retinoids, corticosteroids) are prescribed off-label for HS. Alternative biologics may also be used off-label in patients with more-severe disease who do not respond to Humira (e.g., Janssen’s Stelara). The HS pipeline holds a diverse array of therapies with unique mechanisms of action, such as IL-17 inhibitors (Novartis’s Cosentyx), IL-23 inhibitors (AbbVie’s Skyrizi and Janssen’s Tremfya), IL-1 inhibitors (bermekimab), and JAK-1 inhibitors (INCB054707). If proven efficacious, these agents will enjoy huge commercial opportunity because of the immense unmet need in this space.


  • · What are the key areas of unmet need and opportunity in the HS market?
  • How are patients with different disease severities treated?
  • What is the approximate size of the diagnosed prevalent and incident HS population in the United States? How are cases of HS segmented by severity?
  • What is the expected impact of novel therapies?
  • How does each current and future player influence the market, and how will their influence change in the future?
  • What are the key drivers of and constraints on the HS therapy market?


United States Primary Research 3 KOL interviews in October 2019


AbbVie, Novartis, Janssen, XBiotech, Incyte

Key Drugs Covered

Humira, Cosentyx, Skyrizi, Tremfya, Remicade, Stelara, metformin, spironolactone, clindamycin, rifampicin, bermekimab, INCB054707


Executive Insights provides indication-specific market intelligence with world-class epidemiology, keen insight into current treatment paradigms, biotherapeutic pipelines, key clinical unmet needs, and competitive landscapes, supported by primary and secondary research. This solution provides succinct insights to any biopharma function or business professional looking to quickly grasp a new indication of interest.

launch Related Market Assessment Reports