Human Immunodeficiency Virus – Executive Insights – Human Immunodeficiency Virus Executive Insights

HIV is a deadly viral infection that impairs cells of the immune system and progressively destroys the body’s ability to fight infections. Availability of multiple therapeutic agents for maintaining low viral loads has been fundamental to treatment of HIV. Treatment consists of antiretroviral therapy (ART), and patients are mostly treated with a three-drug pharmacological regimen in combination (often in one pill), with the INSTI-based STRs most prescribed among interviewed KOLs. Among currently available therapies, Biktarvy (BIC/FTC/TAF) is the most preferred drug, except in patients of childbearing age. Newer agents such as Trogarzo (IBA) and Rukobia (FTR) are being used mainly in patients with an MDR infection. Although the most awaited late-phase pipeline agents, Merck & Co.’s islatravir and Gilead Sciences’ lenacapavir, offer a distinct advantage of being longer acting, which will help with long-term adherence to treatment, a cure remains the ultimate goal for treatment of HIV. Discovery and development of latency-reversing agents, immune modulators, and genetically engineered effector antibodies, as well as therapeutic vaccines, will be critical for the future.


  • What is the prevalence of HIV by race / ethnicity or by transmission type? How are U.S. patients managed today for the treatment of HIV?
  • What are the key areas of unmet need and opportunities in the prevention and management of HIV?
  • Which therapies are in late-phase of development for HIV? What is the potential impact of new launches and how will these therapies affect future opportunity in the treatment of HIV?
  • What are the key drivers and limiters of the market today and in the future?


Executive Insights provides indication-specific market intelligence with world-class epidemiology, keen insight into current treatment paradigms, biotherapeutic pipelines, key clinical unmet needs, and competitive landscapes, supported by primary and secondary research. This solution provides succinct insights to any biopharma function or business professional looking to quickly grasp a new indication of interest.

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