Systemic Lupus Erythematosus – Epidemiology – Americas Data
Clarivate Epidemiology’s coverage of systemic lupus erythematosus (SLE) comprises epidemiological estimates of key patient populations in 45 countries worldwide. We report both the incidence and prevalence of SLE for each country, as well as annualized case counts projected to the national population.
Most patient populations are forecast over a period of 20 years for the major mature pharmaceutical markets of the United States, Europe, and Japan and 10 years for the other countries covered.
Clarivate Epidemiology’s SLE forecast will answer the following questions:
- How will changes in the levels of exposure to known risk or protective factors affect the number of people living with a diagnosis of SLE?
- In developing countries, what impact will economic growth and development have on the number of people living with a diagnosis of SLE?
- Of all people diagnosed with SLE, how many in each of the major mature pharmaceutical markets are drug-treated?
- How will demographic trends, such as population aging and improving life expectancy, affect the epidemiology of SLE over the forecast period?
All forecast data are available on the Clarivate Insights Platform in tabular format, with options to download to MS Excel. All populations are accompanied by a comprehensive description of the methods and data sources used, with hyperlinks to external sources. A summary evidence table generated as part of our systematic review of the epidemiological literature is provided for full transparency into research and methods. In addition, we provide a graph of the patient flow between or within different disease states for the countries considered in this report. These patient-flow diagrams are provided at the regional level but may be requested for any specific country or forecast year.
In addition to the total number of cases for each forecast year, Clarivate Epidemiology provides at least 10 years of forecast data for the following SLE subpopulations:
- Diagnosed prevalent cases of SLE characterized by flares, persistently active disease, or both.
- Diagnosed prevalent cases of SLE by lupus nephritis (LN) status.
- Diagnosed prevalent cases of LN by treatment status.
- Diagnosed prevalent cases of nonrenal SLE by treatment status.
Note: Coverage may vary by country.
Table of contents
- Systemic Lupus Erythematosus - Epidemiology - Americas Data
- Introduction
- Key Findings
- Key Updates
- Prevalence of Systemic Lupus Erythematosus Among People of All Ages in 2021 and 2031
- Relative Sizes of the Factors Contributing to the Trend in Prevalent Cases of Systemic Lupus Erythematosus Over the Next 10 Years
- Analysis of the Diagnosed Prevalent Cases of Systemic Lupus Erythematosus in 2021 by Lupus Nephritis Status
- Number of Additional Prevalent Cases of Systemic Lupus Erythematosus in 2031 in the Countries Under Study due to Greater Access to Healthcare and Improved Diagnosis
- Key Findings
- Epidemiology Data
- Methods
- Diagnosed Prevalence
- Diagnosed Prevalence by Comorbid Lupus Nephritis
- Diagnosed Prevalence by Flares and Persistently Active Disease
- Diagnosed Incidence
- Percentage Drug-Treated
- Reference Materials
- Literature Review
- Studies Included in the Analysis of Systemic Lupus Erythematosus
- Studies Excluded From the Analysis of Systemic Lupus Erythematosus
- Risk/Protective Factors
- Risk / Protective Factors for Systemic Lupus Erythematosus
- Bibliography
- Abbreviations
- Glossary
- Literature Review
- Introduction
Sunali D. Goonesekera, S.M., Senior Manager, Epidemiology. Prior to joining Clarivate, Ms. Goonesekera conducted epidemiological research on racial/ethnic disparities in metabolic diseases at the New England Research Institute and lead-authored two manuscripts. She has contributed to multiple publications in peer-reviewed journals in epidemiology and the biological sciences. She holds a master’s degree in epidemiology from the Harvard School of Public Health and a B.A. in biology (Honors) from Dartmouth College.
Rose Buckland, L.L.B., M.Sc., is an associate epidemiologist at Clarivate. While pursuing an M.Sc. in social epidemiology at University College London, she assisted with research into COVID-19 surveillance through the Africa Health Research Institute. She is interested in infectious disease epidemiology, particularly HIV/AIDS. Ms. Buckland holds a postgraduate Bachelor of Law degree from the University of Cape Town in South Africa.