Malignant melanoma is the most aggressive and life-threatening skin cancer, the incidence of which continues to rise despite recent therapeutic advances. Owing to these advances, primarily in immuno- and targeted cancer therapies, the malignant melanoma market has become increasingly crowded with novel treatments expanding therapy options for patients, and segmenting the market according to BRAF-mutation status. While heavily dominated by immune checkpoint inhibitors, such as Merck & Co.’s market-leading Keytruda and Bristol-Myers Squibb/Ono Pharmaceutical’s Opdivo, opportunities exist for novel agents specifically targeting the underpenetrated adjuvant and BRAF wild-type metastatic setting. With a shift toward combination therapy, doublet and triplet therapy, and the introduction of novel agents for later lines, the malignant melanoma treatment algorithm will continue to evolve. In such a dynamic indication, marketed drugs need to be carefully positioned to achieve optimal uptake.
Disease Landscape & Forecast provides comprehensive market intelligence with world-class epidemiology, keen insight into current treatment paradigms, in-depth pipeline assessments, and drug forecasts supported by detailed primary and secondary research.