Epilepsy, which afflicts approximately 4.7 million people in the major markets according to Clarivate epidemiology, is a heterogeneous condition requiring individualized treatment based largely on a patient’s seizure syndrome and seizure type. The market is heavily genericized, and most of the anti-epileptic drugs (AEDs) can be used as monotherapies or in combination. However, recent entrants like cenobamate, fenfluramine, and ganaxolone are carving share in the market, despite being high-priced branded products, by targeting underserved and orphan epilepsy populations. This report provides a detailed account of dynamics in this complex market, including the continued dominance of second-generation AEDs while emerging therapies nevertheless gain traction by addressing unmet needs in this diverse patient population.
Markets covered: United States, France, Germany, Italy, Spain, United Kingdom, Japan.
Primary research: Approximately 20 country-specific interviews with thought-leading neurologists, supported by survey data collected for this content and other Clarivate research.
Epidemiology: Diagnosed prevalence of epilepsy by country, segmented by generalized and partial-onset seizures; drug-treated cases.
Emerging therapies: Phase II: 12 drugs; Phase III / preregistration: 6 drugs.
Market forecast features: Patient-based market forecast extending through 2032, segmented by brands and generics / biosimilars.
Disease Landscape & Forecast provides comprehensive market intelligence with world-class epidemiology, keen insight into current treatment paradigms, in-depth pipeline assessments, and drug forecasts supported by detailed primary and secondary research.
Disease Landscape & Forecast will be updated throughout the year to provide timely insights and analyses as material indication-specific news and events unfold.
Disease Landscape & Forecast features a Drug Pipeline chapter with real-time, global pipeline intelligence content directly from Cortellis. This chapter is updated daily and features interactive figures that can be easily downloaded for detailed analysis or presentations.