The schizophrenia therapy market is crowded and dominated by atypical and typical antipsychotics. Although the continued generic erosion of oral atypical antipsychotics influences psychiatrists’ treatment decisions (e.g., the recent availability of generic lurasidone in the United States), newer oral atypical antipsychotics (e.g., Alkermes’s Lybalvi, Intra-Cellular Therapies’ Caplyta), along with drugs such as BioXcel Therapeutics’ Igalmi, are aiming to make inroads into the treatment pathway. Competition between long-acting injectables (LAIs) is also intensifying with the availability of new therapies (e.g., Janssen’s Invega Hafyera, Lundbeck / Otsuka’s Abilify Asimtufii, Teva’s Uzedy), along with the generic availability of some key LAIs. Nevertheless, novel drugs targeting key unmet needs will be welcomed (e.g., Boehringer Ingelheim’s iclepertin for cognitive impairment in schizophrenia, Acadia’s Nuplazid for the negative symptoms of schizophrenia), but other therapies in late-phase development (e.g., Karuna’s KarXT, Newron Pharmaceuticals’ evenamide) will have to clearly differentiate themselves from established therapies to gain a strong foothold in this market. As such, a deep understanding of the current and future dynamics in the schizophrenia therapy market is critical.
Geographies: United States, EU5, Japan
Primary research: 33 country-specific interviews with thought-leading psychiatrists, supported by survey data collected for this and other Clarivate research
Epidemiology: Diagnosed prevalence of schizophrenia by country, segmented by positive symptoms, negative symptoms, and cognitive impairment; drug-treated prevalence of schizophrenia by country
Forecast: 10-year, annualized, drug-level sales and patient share of key schizophrenia therapies through 2032, segmented by brands/generics
Emerging therapies: Phase 3 / PR: 11 drugs; coverage of select early-phase products
Disease Landscape & Forecast provides comprehensive market intelligence with world-class epidemiology, keen insight into current treatment paradigms, in-depth pipeline assessments, and drug forecasts supported by detailed primary and secondary research.
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