Human Immunodeficiency Virus – Current treatment – Detailed, Expanded Analysis (US)

The human immunodeficiency virus (HIV) therapy market is dynamic and growing. With the launches of many effective antiretroviral therapies (ARTs), such as Gilead’s Biktarvy and ViiV’s Dovato, Juluca, and Cabenuva (long-acting once-monthly injection), safety and tolerability have become the key differentiating attributes among ART regimens. For most patients, current ARTs such as single-tablet regimens (STRs) have achieved maximal antiretroviral efficacy and tolerability, changing HIV infection from a fatal disease to a tolerable chronic condition. Despite this achievement, adherence to regular oral medicine consumption remains a problem; however, the recent label expansion of Cabenuva, a novel medication delivery strategy, is poised to transform the treatment landscape, reducing the once-daily pill burden to only six intramuscular injections each year. Other recently approved long-acting options that address the adherence burden, such as Gilead’s Sunlenca for heavily treatment-experienced patients with multidrug-resistant HIV-1 infection, also aim to transform the treatment landscape. This report focuses on current treatment and the anticipated use of HIV treatment regimens by capturing patient market share data, current prescribing trends, and anticipated changes in prescribing and treatment behavior. The key prescribing drivers and barriers, and salesforce performance for key brands, will be evaluated. This content will quantitatively explore the current treatment of HIV as marketed ARTs and novel agents advance in the pipeline.

Questions answered

  • Which comorbidities are most common among surveyed physicians’ patient populations?
  • How do physicians approach the management of newly diagnosed HIV patients and those switching treatment?
  • Which patients receive which ART based on their CD4 count level?
  • Which patients are being prescribed STRs (e.g., Gilead’s Biktarvy, Genvoya, and Odefsey; ViiV’s Juluca and Dovato) and in which line(s) of therapy? What factors drive the movement of HIV patients through lines of therapy?
  • Which ARTs are the patient-share leaders in HIV? How are key STRs positioned in surveyed physicians’ treatment algorithms?
  • What is the sequencing of treatment for HIV?
  • What are the most influential drivers of treatment selection for HIV?
  • What are the infectious disease physician-reported factors determining current prescribing patterns and recent / anticipated changes?

Content highlights

Geography: United States

Key drugs covered: Biktarvy, Dovato, Juluca, Cabenuva

Product description

Current Treatment: Physician Insights provides physician insights on treatment dynamics, prescribing behaviour, and drivers of brand use so that marketers can create specific messaging around these treatment dynamics to more effectively increase or defend their market position.

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