Migraine – Current Treatment – Detailed, Expanded Analysis (EU5)
According to DRG epidemiology, over 30 million people in the EU5 suffer migraines and over 10% of migraineurs suffer chronic migraine. Migraine prophylaxis is a core treatment approach for high-frequency episodic and chronic migraine patients to reduce migraine frequency, severity, and duration. Current drug treatment primarily includes a mix of off-label and approved antiepileptic drugs, beta blockers, tricyclic antidepressants, Botox (Allergan’s onabotulinumtoxinA), and—now—multiple anti-CGRP monoclonal antibodies (MAbs), the first migraine-specific preventive brands. With many agents to choose from and a heterogeneous patient population, prophylactic treatment is individualized, complex, and evolves over time. Understanding patient pathways and drivers of treatment decision-making is key for new players bringing novel brands to this large and underserved, but mostly generic, market.
QUESTIONS ANSWERED
What patient share do oral standards of care and injectable brands garner overall, and by line of therapy, in migraine patients treated with prophylaxis?
What are the drivers and constraints influencing physicians’ treatment decisions and choice of therapy for migraine prophylaxis across the EU5?
What role do Botox and the anti-CGRP MAbs play in the evolving treatment algorithm? Which MAb garners the most use, and why?
What percentage of migraine patients are treated with monotherapy versus combination therapy? How long are migraineurs treated with prophylaxis?
PRODUCT DESCRIPTION
Current Treatment: Physician Insightsprovides physician insights on treatment dynamics, prescribing behavior, and drivers of brand use so that marketers can create specific messaging around these treatment dynamics to more effectively increase or defend their market position.
Migraine - Current Treatment - Detailed, Expanded Analysis (EU5)
Current Treatment Physician Insights Migraine Prophylaxis EU5 November 2020
Meher Baba Kumar Nakka
Meher Baba Kumar Nakka, M.S.(Pharm.), is an analyst on the CNS/Ophthalmology Disorders team at Clarivate. In this capacity, he works on a range of neurological indications, such as pain and migraine, and neurodegenerative disorders, such as Alzheimer’s disease. He holds a bachelor’s degree in pharmacy from Jawaharlal Nehru Technological University in Hyderabad and a master’s degree in pharmacoinformatics from the National Institute of Pharmaceutical Education and Research in Mohali.
Jonathan Searles
Jonathan W. Searles is a senior director on the CNS/Ophthalmology Disorders team at Clarivate. In this role, he oversees the team’s syndicated research stream in neurology, with a core focus on multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, epilepsy, migraine, and ischemic stroke. He earned his bachelor’s degree at Brandeis University, where he graduated summa cum laude.
