China has the highest incidence of gastroesophageal cancer globally, and therapeutic options are limited. Only five targeted agents are approved to treat this indication—Roche’s Herceptin as the first-line standard of care for HER2-positive gastric and GEJ adenocarcinoma patients, Jiangsu Hengrui Medicine’s AiTan and BMS’s Opdivo for third-line gastric and GEJ adenocarcinoma patients, and Merck’s Keytruda and Jiangsu Hengrui Medicine’s AiRuiKa for second-line esophageal squamous cell carcinoma patients. Several novel targeted therapies—including VEGF2 inhibitors (Eli Lilly’s Cyramza and Chi-Med’s Elunate), a claudin inhibitor (Ganymed’s zolbetuximab), and immune checkpoint inhibitors (Innovent Biologics’ Tyvyt, BeiGene’s Baizean, and CStone Pharmaceuticals’s CS1001)—are in preregistration or late-phase trials. The launch and uptake of these agents will lead to significant growth of the gastroesophageal cancer therapy market over the 2020-2030 period. However, the need for additional, effective targeted therapies will remain high, representing a lucrative commercial opportunity for developers.
· How large is China’s drug-treatable gastroesophageal cancer population, and how will drug-treatment rates change during the forecast period?
· Which are the most commercially relevant drugs in China’s gastroesophageal cancer market and why? What are interviewed experts’ insights into current treatment options?
· What are the key market access considerations for therapies in the gastroesophageal cancer pipeline in China? What sales / uptake could they secure in gastroesophageal cancer? What are interviewed experts’ opinions of key emerging therapies?
· What are the key drivers and constraints in the gastroesophageal cancer therapy market of China, and how will the market evolve over the forecast period?
China In-Depth offers comprehensive market intelligence, including world-class epidemiology, keen insight into the China-specific A&R environment, current treatment paradigms, in-depth pipeline assessments, and drug forecasts supported by detailed primary and secondary research. This solution helps companies gauge commercial outlooks and optimize clinical development, subpopulation targeting, physician messaging, and overall long-term strategy in China.