Asthma | Treatment Algorithms: Claims Data Analysis | Pediatric Asthma | US | 2020

Pediatric asthma is treated using two types of pharmacotherapies: rescue therapy for acute symptoms via bronchodilation (e.g., a SABA) and maintenance therapy to prevent exacerbations by targeting underlying pathophysiology (e.g., a LABA/ICS, such as GSK’s Advair or AstraZeneca’s Symbicort); most pediatric asthma patients receive more than one agent to treat their condition. Despite the availability of multiple, well-established therapies, the pediatric asthma treatment landscape has seen the approval and launch of additional agents in recent years, including salmeterol / fluticasone generics and novel biological drugs (e.g., Regeneron / Sanofi’s Dupixent, GSK’s Nucala). These events have added more treatment options and fueled competition in this market.

QUESTIONS ANSWERED

  • What patient shares do key therapies and brands garner by line of therapy in newly diagnosed pediatric asthma patients?
  • What are the quarterly trends in prescribing among recently treated and newly diagnosed pediatric asthma patients?
  •  How have newer biological therapies, such as AstraZeneca’s Fasenra, been integrated into the treatment algorithm, and what are their sources of business?
  •  What percentage of pediatric asthma patients receive drug therapy within 365 days of diagnosis, and how quickly?
  • What percentage of patients progress to later lines of therapy within 365 days of diagnosis?
  • What percentage of pediatric asthma patients are treated with monotherapy versus combination therapy?
  • What are the most commonly used combinations?
  • What are the product-level compliance and persistency rates among drug-treated patients?

Geographies

  • United States

Real world data

  •  Longitudinal patient-level claims data analysis

Key drugs covered:

  • Advair, Symbicort, Dulera, Breo, Fasenra, Nucala, Xolair, Ventolin, ProAir, montelukast sodium, Flovent, Spiriva

Key analysis provided

  • Brand/therapy usage across longitudinal patient sample
  • Newly diagnosed patient analysis
  • Treatment initiation and progression
  • Line of therapy analysis
  • Combination therapy analysis
  • Source of business for recently treated patients
  • Persistency and compliance analysis

PRODUCT DESCRIPTION

Treatment Algorithms: Claims Data Analysis provides detailed, quantitative analysis of the treatment journey and brand usage across lines of therapy and overall using real-world, patient-level claims data so that marketers can accurately assess their source of business, benchmark usage against competitors, and quantify areas of opportunity for their marketed or emerging brand.

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