DRG epidemiologists estimate that 60% of epilepsy patients experience partial-onset seizures (POS), which aretypically the gateway indication for new antiepileptic drugs (AEDs). The most frequently prescribed early-line treatments for POS are generic mainstays, such as levetiracetam, lamotrigine, and carbamazepine/oxcarbazepine; newer brands such as Vimpat and Briviact are prescribed in later lines of therapy, mostly to treatment-refractory patients. Neurologists consider many factors when selecting among the many first-, second-, and third-generation AEDs and make adjustments throughout a patient’s disease course to achieve optimal seizure control. Understanding the evolving journey of epilepsy patients with POS provides important context about the complex, saturated, and heavily generic market that developers of new AEDs will enter. For the first time, our 2019 Treatment Algorithms series offers this POS segmentation, as well as a companion study on generalized-onset seizures (GOS).
Markets covered: United States
Real-world data: Longitudinal patient-level claims data analysis
Key companies: Sunovion Pharmaceuticals, Eisai, UCB, Pfizer, Janssen, and Concordia Pharmaceuticals
Key drugs covered: Vimpat, Aptiom, Briviact, Fycompa, Lyrica, levetiracetam, lamotrigine, carbamazepine, oxcarbazepine, valproates
Key analysis provided:
Treatment Algorithms: Claims Data Analysis provides detailed, quantitative analysis of the treatment journey and brand usage across lines of therapy and overall using real-world, patient-level claims data so that marketers can accurately assess their source of business, benchmark usage against competitors, and quantify areas of opportunity for their marketed or emerging brand.