A subset of major depressive disorder (MDD) patients experience suicidal ideation (SID). Because of the potential lethality of SID, SID in MDD is a highly drug-treated condition that uses an array of drug classes including, but not limited to, selective serotonin reuptake inhibitors (SSRIs), benzodiazepines, and—as adjunctive therapies—atypical antipsychotics. Such therapies are intended to treat MDD and, by extension, address SID. Even though the drug market is entrenched with generic therapies, MDD patients’ heterogeneous responses to a treatment give branded drugs (e.g., Trintellix [Lundbeck/Takeda], Rexulti [Otsuka/Lundbeck]) the opportunity for use, often as later-line therapies. Given MDD’s crowded and competitive landscape, drug marketers and developers will find value in understanding how MDD patients with SID are being treated based on real-world data.
Treatment Algorithms: Claims Data Analysis provides detailed analysis of brand use across different lines of therapy using real-world patient-level claims data so that clients can accurately assess their source of business and quantify areas of opportunity for increasing their brand share.
Markets covered: United States
Real-world data: Longitudinal patient-level claims data analysis
Key companies: Otsuka, Lundbeck, Takeda, Allergan
Key drugs: Aripiprazole (Abilify, generics), citalopram, trazodone, Fetzima, Rexulti, Trintellix, Viibryd
Key analysis provided: