Ovarian Cancer – Access & Reimbursement – Detailed, Expanded Analysis (US)

The premium-priced therapies used to treat ovarian cancer, such as Avastin (Roche/Genentech) and the PARP inhibitors Lynparza (AstraZeneca/Merck & Co), Rubraca (Clovis Oncology), and Zejula (GlaxoSmithKline/Tesaro), result in a significant financial burden for payers. These costs are likely to increase with the expected label expansions of current therapies to new patient populations and the anticipated approval of AstraZeneca’s Imfinzi for newly diagnosed advanced ovarian cancer. As the number of high-priced therapies increases, understanding the market access drivers that are important to payers and oncologists will be essential to maximizing these therapies’ uptake.


  • How are Avastin and the PARP inhibitors positioned in the treatment algorithm? How have PARP inhibitors been adopted into physician prescribing patterns?
  • What is the formulary coverage of key brands for ovarian cancer, and what types of cost control have MCOs enacted?
  • What role does value assessment play in MCOs’ review of ovarian cancer drugs? Which types of information do MCOs use in their assessment?
  • What are physicians’ views on the key emerging therapies for ovarian cancer? What factors will most influence MCO coverage of an early-line PARP inhibitor-based therapy?


United States


  • Survey of 100 U.S. medical oncologists.
  • Survey of 30 U.S. managed care organization (MCO) pharmacy and medical directors (PDs/MDs).


Avastin, Lynparza, Rubraca, Zejula, Imfinzi


  • Reimbursement and contracting.
  • Access and prescribing.
  • Special topics.
  • Opportunities and challenges for emerging therapies.


U.S. Access & Reimbursement provides in-depth insight on the impact of payer policy on prescribing behavior so that clients can build their market access strategy and optimize their brand positioning. This analysis of primary market research with physician specialists and U.S. payers helps clients stay up-to-date on restriction policies, gauge payer and prescriber attitudes toward specific therapies, identify opportunities where brands can capture patient share through market access, and maximize opportunities for emerging therapies by learning how previous brands gained favorable reimbursement or why they stumbled.

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