Comparative Target Safety Evidence
This is the first of a series of new analytics that will be developed leveraging our unique OFF-X Target/Class Score, a measure of the evidence available in OFF-X for each Target-Action-Adverse Event association.
- Compare the safety profiles of different targets for the same indication
- Identify potential advantages in terms of safety for repurposed targets
- Anticipate the potential safety issues of novel compounds (even before animal testing) based on their experimental secondary pharmacology profile
- Identify toxicities that could be exacerbated by targeting different pathways via new drug combinations
