Renal anemia is a common complication of chronic kidney disease (CKD). Although there are treatments for the disease, physicians, patients, and healthcare systems have concerns about their limitations. Delivery, safety issues, and tightening healthcare budgets have resulted in increased scrutiny of the effectiveness and tolerability of such therapies as intravenous (IV) iron and erythropoiesis-stimulating agents (ESAs). The renal anemia therapy market will expand over the 2021-2031 study period, fueled by increasing prevalence and demand for new drugs that can effectively, safely, and conveniently control the disease. The launches of several hypoxia-inducible factor-prolyl hydroxylase (HIF-PH) inhibitors are expected during the study period. Although these new therapies offer advantages over current therapies, they will face major challenges, including reimbursement hurdles and an increasingly stringent regulatory environment.
QUESTIONS ANSWERED
What are the opportunities for marketers of the emerging oral HIF-PH inhibitors to promote their noninvasive route of administration, particularly for patients not on dialysis?
Will establishing cardiovascular (CV) safety be key for the market uptake of HIF-PH inhibitors, in view of the CV issues associated with current therapies?
With the imminent availability of biosimilars in the United States, how will emerging therapies that offer only incremental improvements over existing therapies fare?
CONTENT HIGHLIGHTS
Markets covered: United States, France, Germany, Italy, Spain, United Kingdom, Japan.
Primary research: 20 country-specific interviews with thought-leading nephrologists. Supported by survey data collected for this and other Clarivate research.
Epidemiology: Prevalence of renal anemia by country and diagnosed / drug-treated rates.
Emerging therapies: Coverage of select emerging therapies from preclinical to preregistration stages.
Market forecast features: 10-year, annualized, drug-level sales and patient share of key renal anemia therapies through 2031, segmented by brands / generics.
PRODUCT DESCRIPTION
Disease Landscape & Forecast provides comprehensive market intelligence with world-class epidemiology, keen insight into current treatment paradigms, in-depth pipeline assessments, and drug forecasts supported by detailed primary and secondary research.
SOLUTION ENHANCEMENT
Disease Landscape & Forecast will feature continuous updates in 2023 to provide timely insights and analyses as meaningful indication-specific news and events unfold.
Factors influencing drug selection in renal anemia
Treatment decision tree for renal anemia: United States
Treatment decision tree for renal anemia: Europe
Treatment decision tree for renal anemia: Japan
Unmet need overview
Current and future attainment of unmet needs in renal anemia
Top unmet needs in renal anemia: current and future attainment
Expert insight: unmet need in renal anemia
Emerging therapies
Key findings
Key emerging therapies
Key therapies in development for renal anemia
Estimated launch dates of key emerging therapies for the treatment of renal anemia
Daprodustat profile
Analysis of the clinical development program for daprodustat
Expert insight: daprodustat
Expectations for launch and sales opportunity of daprodustat in renal anemia
Early-phase pipeline analysis
Select compounds in early-phase development for renal anemia
Access & reimbursement overview
Region-specific reimbursement practices
Key market access considerations in renal anemia: United States
General reimbursement environment: United States
Key market access considerations in renal anemia: EU5
General reimbursement environment: EU5
Key market access considerations in renal anemia: Japan
General reimbursement environment: Japan
Appendix
Abbreviation
Renal anemia bibliography
Tej Pal, M.Pharm.
Tej Pal, M.Pharm., is a senior healthcare research & data analyst on the Cardiovascular, Metabolic, Renal, and Hematologic Diseases team at Clarivate. He has authored several reports focusing on metabolic and renal indications. Previously, he was an analyst at IQVIA and at Smart Analyst Inc., where he worked closely with top pharmaceutical companies on commercial and technical ad-hoc requests. During his tenure there, he delivered competitive landscape and market insight projects on various oncology indications. He holds a master’s degree in pharmacy with a specialization in pharmaceutical chemistry from the Delhi Institute of Pharmaceutical Sciences and Research in New Delhi, India.