The hemophilia A treatment landscape has evolved with the acceptance of Roche / Chugai’s nonfactor bispecific antibody Hemlibra as a key treatment. Offering improved treatment outcomes, Hemlibra has been transformative for many inhibitor patients who were on bypass agent prophylaxis. Also, with its reduced dosing frequency and subcutaneous administration, it is a more-convenient prophylaxis option for noninhibitor patients. The next five to ten years will be exciting for the hemophilia A (with and without inhibitors) therapy market owing to the entry of an extended half-life factor VIII product (Sanofi’s BIVV001), several nonfactor agents (Sanofi’s fitusiran, Pfizer’s marstacimab, and Novo Nordisk’s concizumab and mim8), and gene therapies (BioMarin’s Roctavian, Pfizer / Sangamo Therapeutics’ giroctocogene fitelparvovec). Supported by insights from thought leaders, we assess the impact of new drug therapies on the treatment of hemophilia A.
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Disease Landscape & Forecast provides comprehensive market intelligence with world-class epidemiology, keen insight into current treatment paradigms, in-depth pipeline assessments, and drug forecasts supported by detailed primary and secondary research.
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Disease Landscape & Forecast will be updated throughout the year to provide timely insights and analyses as material indication-specific news and events unfold.
Disease Landscape & Forecast features a Drug Pipeline chapter with real-time, global pipeline intelligence content directly from Cortellis. This chapter is updated daily and features interactive figures that can be easily downloaded for detailed analysis or presentations.