1. Marketed by Novartis Pharmaceuticals Corporation (United States and European Union) and GlaxoSmithKline plc (Japan)
  2. Selective multi-targeted receptor tyrosine kinase inhibitor
  3. Treatment of advanced renal cell carcinoma (RCC) and advanced soft tissue sarcoma


  1. First E.U. approval: June 14, 2010
  2. First U.S. approval: October 19, 2009

Constraint date forecast:

  1. Patent expiry: 2023 (United States)
  2. SPC expiries: 2025 (European Union)
  3. Patent expiry: 2027 (Japan)

The future of the generics landscape

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