Product logins

Find logins to all Clarivate products below.


IL -17 inhibitors have established a high standard for efficacy in moderate to severe psoriasis, placing pressure on current therapies that are less efficacious and a great number of investigational therapies that are still in the pipeline. While dermatologists are becoming more comfortable prescribing an IL -17 inhibitor before TNF inhibitors, Humira, a TNF inhibitor, remains the most prescribed therapy in this highly competitive market. However, opportunity exists for emerging therapies to differentiate themselves by addressing important unmet needs that are identified in this analysis.
Questions Answered:

What are the treatment drivers and goals for moderate to severe psoriasis?
What attributes are key influencers, which have limited impact, and which are hidden opportunities?
How do current therapies perform on key treatment drivers and goals for moderate to severe psoriasis?
What are the prevailing areas of unmet need and opportunity in moderate to severe psoriasis?
What trade-offs across different clinical attributes and price are acceptable to and European dermatologists for a hypothetical new moderate to severe psoriasis drug?

Markets covered: United States, United Kingdom, France, Germany
Primary research: Survey of 60  and 30 European dermatologists fielded in February and March 2017
Key companies:   AbbVie, Amgen, Celgene, Eli Lilly, Janssen, Merck, Novartis
Key drugs:  Cosentyx, Enbrel, Humira, Otezla, Remicade, Stelara, Taltz

Related Market Assessment Reports

Report
Multiple Myeloma – Current Treatment – Treatment Sequencing – Multiple Myeloma (US)
Key benefits and usesPinpoint current drug positioning and uptake in one snapshot to facilitate forecasting.Drill down into physicians’ treatment sequences and understand who to position against…
Report
Epilepsy – Unmet Need – Unmet Need – Dravet Syndrome (US/EU)
Dravet syndrome (DS) is a rare, severe, pediatric-onset genetic epileptic encephalopathy that typically emerges within the first year of life and is marked by developmental delays and multiple…
Report
Alzheimer’s Disease – Unmet Need – Unmet Need – Agitation in Alzheimer’s Disease (US/EU)
Agitation affects most Alzheimer’s disease (AD) patients and comprises a constellation of disruptive symptoms for patients and their families, which may contribute to nursing home placement…
Report
Breast Cancer – Unmet Need – Unmet Need – Metastatic HR-Positive / HER2-Negative Breast Cancer (US/EU)
The landscape of advanced HR-positive / HER2-negative breast cancer treatment is continually evolving. CDK4/6 inhibitors (Pfizer’s Ibrance, Novartis’s Kisqali, and Eli Lilly’s Verzenio)…
Report
Hepatitis B Virus – Geographic Focus: China – China In-Depth – Hepatitis B Virus
HBV is a major public health burden in China, with chronically infected individuals at a significantly increased risk of developing hepatic cirrhosis and hepatocellular carcinoma. Current treatment…