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Type 1 Diabetes – Current Treatment – Treatment Algorithms: Claims Data Analysis – Type 1 Diabetes (US)

Intensive insulin regimens have proven effective in delaying the progression of complications associated with untreated or poorly treated type 1 diabetes (T1D). Thus, insulins remain the cornerstone of T1D market being the primary treatment option for disease management, with long-acting and rapid-acting insulins leading the patient-share in the United States. The selection of branded insulin, choice of regimen, and order in which brands and/or regimens are attempted vary. In addition, the introduction of biosimilar/interchangeable insulins has added complexity to the T1D therapy market. The growing adoption of insulin pumps is also significantly shaping the evolving T1D market landscape. 

Questions answered

  • What patient shares do key therapies garner by line of therapy in newly diagnosed T1D patients? What are the quarterly trends in prescribing among recently treated and newly diagnosed T1D patients?
  • How have ultra-rapid-acting insulins (insulin aspart and insulin lispro-aabc) been integrated into the treatment algorithm, and what are their sources of business?
  • What percentage of T1D patients receive drug therapy within one year of diagnosis, and how quickly? What percentage of patients progress to later lines of therapy within one year of diagnosis?
  • What percentage of T1D patients are treated with monotherapy vs. combination therapy? What are the most commonly used combinations?
  • What are the product-level persistence and compliance rates among drug-treated patients?

Geography: United States

Real-world data: Patient-level claims data analysis

Key drugs: Insulin glargine (U100), insulin degludec, insulin aspart, insulin lispro, premixed insulins

Key analyses: Brand / therapy usage across longitudinal patient sample; Newly diagnosed patient analysis; Treatment initiation and progression; Line of therapy analysis; Combination therapy analysis; Source of business for recently treated patients; Persistency and compliance analysis; Product-level patient flow charts

Key feature: Dashboard featuring interactive visuals, easy navigation, and expanded analyses

Product description

Treatment Algorithms: Claims Data Analysis provides detailed, quantitative analysis of the treatment journey and brand usage across lines of therapy and overall using real-world, patient-level claims data, enabling you to:

  • Understand patient flow between lines of therapy.
  • Evaluate your brand share against competitors.
  • Accurately assess your source of business.
  • Quantify opportunities at different stages of the treatment algorithm.

Product enhancement

Treatment Algorithms: Claims Data Analysis leverages Clarivate’s proprietary Real-World Data, which brings larger patient samples, broader payer coverage, and faster availability for more robust and timely analyses. Additionally, we include new patient demographic analyses: age, gender, ethnicity, and region.

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