Sjögren’s Syndrome | Niche & Rare Disease Landscape & Forecast | US/EU5 | 2022
Sjögren’s syndrome (SS) is a progressive autoimmune disease characterized by chronic inflammation and lymphocytic infiltration of the exocrine glands; the disease may occur alone (primary SS) or with a comorbid autoimmune condition (secondary SS). Symptomatic therapies to treat dry eyes, dry mouth, and/or specific extraglandular manifestations are the cornerstone of disease management. Systemic manifestations are most often treated with hydroxychloroquine or, in severe cases, systemic immunomodulators (e.g., azathioprine, methotrexate). Therapies with disease-modifying potential are in development for SS (e.g., Novartis’s iscalimab and ianalumab), targeting key pathways believed to drive pathological processes in the disease. These putative disease-modifying therapies have the potential to transform the management of SS, although SS is an indication in which such success has historically been a challenge.
Questions answered
- How large is the SS population and how will its size change over time?
- How is SS currently managed? What are the current treatments, and what drives their use?
- Which unfulfilled clinical needs are the most pressing?
- Which pipeline products are the most promising, and what sales might they garner in the SS market? What therapies of note are progressing in earlier phases?
- What clinical roles will Novartis’s iscalimab and ianalumab play in the evolving SS treatment landscape?
- What are the drivers of and constraints in the SS market, and how will the market evolve through 2031?
Content highlights
- Geographies: United States and EU5.
- Primary research: Six country-specific interviews with thought-leading SS specialists supported by survey data collected for this study.
- Epidemiology: Diagnosed and drug-treated prevalent cases of SS by country, diagnosed prevalence by subtype.
- Forecast: Drug-level sales and patient share of key SS therapies through 2031.
- Emerging therapies: Phase III/PR: 1 drug; Phase II: 7+ drugs; coverage of select early-phase products.
Product description
Niche & Rare Disease Landscape & Forecast provides comprehensive market intelligence with world-class epidemiology, keen insight into current treatment paradigms, in-depth pipeline assessments, and drug forecasts supported by detailed primary and secondary research.
Solution enhancement
Niche & Rare Disease Landscape & Forecast introduces a new Drug Pipeline chapter with real-time, global pipeline intelligence content directly from Cortellis. This chapter is updated daily and features interactive figures that can be easily downloaded for detailed analysis or presentations.
