Product logins

Find logins to all Clarivate products below.


Gastroesophageal Cancer – Current Treatment – Current Treatment: Physician Insights – Gastroesophageal Cancer (US)

The gastroesophageal cancer therapy market is gaining a lot of traction. In the HER2-positive segment, trastuzumab-based regimens, with or without Keytruda, continue to dominate. Meanwhile, the HER2-negative setting is on the brink of a significant transformation. Immune checkpoint inhibitors such as Opdivo and Keytruda have achieved unparalleled penetration into all populations and lines of therapy. The FDA’s anticipated restriction of PD-1 inhibitors to PD-L1-expressing tumors, coupled with the approval of the first-in-class claudin 18.2 inhibitor Vyloy, will further reshape market dynamics in this space.

QUESTIONS ANSWERED

  • What are the treatment rates for gastroesophageal cancer in the various settings and lines of therapy?
  • What is Vyloy’s impact on the HER2-negative gastroesophageal cancer market?
  • What are the leading therapies in the treatment of HER2-positive gastroesophageal cancer?
  • What do surveyed oncologists consider the main drivers of and key obstacles to the uptake of select therapies?

PRODUCT DESCRIPTION

Through survey data from U.S. physicians, Current Treatment: Physician Insights offers in-depth analyses of the reasons behind treatment dynamics, prescribing behavior, and brand preference, enabling you to:

  • Understand the treatment landscape for a disease and how physicians make prescribing decisions.
  • Evaluate the drivers and obstacles that influence treatment selection.
  • Analyze your brand’s performance from the physician perspective to enhance or defend your competitive position.
  • Create impactful messaging for physicians by identifying brand differentiators and understanding what motivates prescribing behaviors.

Markets covered: United States

Primary research: Survey of 100 medical oncologists in the United States fielded in April 2025.

Key drugs: Cyramza, Enhertu, Herceptin, Keytruda, Lonsurf, Opdivo, Tevimbra, Vyloy, Yervoy

Related Market Assessment Reports

Report
Hemophilia A – Current Treatment – Current Treatment: Physician Insights – Hemophilia A with Inhibitors (US)
Development of neutralizing antibodies against factor VIII replacement is the most significant clinical complication in hemophilia A, necessitating specialized and often high-cost management…
Report
Major Depressive Disorder (DSM-V) – Access & Reimbursement – Access & Reimbursement – Major Depressive Disorder (US)
Numerous drugs from multiple drug classes are used as monotherapies and/or adjunctive therapies to treat major depressive disorder (MDD). Early-line treatment is dominated by generically available…
Report
Malignant Melanoma – Unmet Need – Unmet Need – BRAF Wild-Type, Unresectable or Metastatic Malignant Melanoma (US/EU)
Treatment for BRAF wild-type unresectable or metastatic melanoma has been largely shaped by the successive approvals of immune checkpoint inhibitors. Anti-PD-1 agents such as Keytruda (Merck & Co…
Report
Systemic Lupus Erythematosus – Unmet Need – Unmet Need – Moderate to Severe Systemic Lupus Erythematosus (US/EU)
Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect different organ systems of the body and manifest in a wide range of clinical symptoms, from general fatigue to serious…
Report
Systemic Lupus Erythematosus | Unmet Need | Moderate to Severe Systemic Lupus Erythematosus | US/EU | 2024
Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect different organ systems of the body and manifest in a wide range of clinical symptoms, from general fatigue to serious…