Product logins

Find logins to all Clarivate products below.


Renal Cell Carcinoma | Current Treatment: Physician Insights | US | 2019

The treatment of renal cell carcinoma has long been dominated by targeted treatments, including mTOR and angiogenesis inhibitors. However, the introduction of immune checkpoint inhibitors has diversified treatment options. The treatment landscape for renal cell carcinoma is rapidly moving toward combination combinatorial approaches, as witnessed by the approvals of Lenvima/Kisplyx (Eisai) plus Afinitor (Novartis) in 2016, Opdivo plus Yervoy (Bristol-Myers Squibb/Ono Pharmaceutical) in 2018, and Keytruda (Merck & Co.) plus Inlyta (Pfizer) in 2019. As combination regimens experience uptake in the larger and more commercially lucrative first-line advanced setting, drug developers should gain an understanding of the key drivers and obstacles to maximize uptake.

Questions Answered

  • What are the drug-treatment rates across clinically and commercially relevant renal cell carcinoma patient populations?
  • How are the new drug entrants performing in the face of existing small-molecule TKIs such as Votrient and Sutent for advanced disease?
  • What is the uptake of Opdivo plus Yervoy in previously untreated intermediate- or poor-risk advanced renal cell carcinoma, according to U.S. medical oncologists?
  • What factors drive or constrain the prescribing habits of U.S. medical oncologists?

Product Description

Current Treatment: Physician Insights provides physician insights on treatment dynamics, prescribing behavior, and drivers of brand use so that marketers can create specific messaging around these treatment dynamics to more effectively increase or defend their market position.

Geographies: United States

Primary Research: Survey of 100 medical oncologists in the United States

Key Ddrugs Ccovered: Opdivo, Yervoy, Cabometyx, Sutent, Votrient, Inlyta, Afinitor, Lenvima

Related Market Assessment Reports

Report
Eosinophilic Esophagitis – Unmet Need – Unmet Need – Eosinophilic Esophagitis (US/EU)
Standard treatments for eosinophilic esophagitis (EoE) typically include proton pump inhibitors (PPIs) and swallowed topical steroids. Although these therapies can alleviate EoE symptoms, their…
Report
Breast Cancer – Geographic Focus: China – China In-Depth – Breast Cancer
China’s breast cancer market continues to evolve rapidly, driven by rising incidence and expanding systemic treatment options. Several new and emerging therapies are expected to gain approval for…
Report
Chronic Obstructive Pulmonary Disease – Unmet Need – Unmet Need – Severe to Very Severe Chronic Obstructive Pulmonary Disease (US EU)
The severe to very severe chronic COPD market is crowded, with numerous LAMA, LABA/ICS, LABA/LAMA, and triple LABA/LAMA/ICS inhalers competing for use. Although dual and triple longacting…
Report
Diabetic Macular Edema / Diabetic Retinopathy – Current Treatment – Treatment Algorithms: Claims Data Analysis – Diabetic Macular Edema (US)
Diabetic macular edema (DME) is a serious complication of diabetic retinopathy caused by persistently elevated blood glucose levels. Without timely treatment, DME can progress to significant vision…
Report
Multiple System Atrophy – Unmet Need – Multiple System Atrophy (US/EU) – Unmet Need – Multiple System Atrophy (US/EU)
Multiple system atrophy (MSA) is a rare, rapidly progressing neurodegenerative synucleinopathy that disrupts movement, balance, and autonomic function. Current management comprises only symptomatic…