Gout – Current Treatment – Treatment Algorithms: Claims Data Analysis – Gout (US)

Gout is a form of inflammatory arthritis caused by sustained hyperuricemia, or elevated serum uric acid (sUA) levels. This condition manifests through sudden and intense gout flares, causing significant discomfort. The therapeutic approach for acute flares differs from chronic gout management, and it is not the focus of this analysis. Chronic treatment aims to prevent recurrent gout attacks and limit joint damage by lowering sUA levels. Xanthine oxidase inhibitors (XOIs), especially the widely prescribed generic allopurinol, form the cornerstone of chronic gout treatment. For later lines of therapy, pegloticase (Krystexxa), a highly efficacious biological agent, is utilized. This report provides valuable insights into the use of these treatments in patients with newly diagnosed or recently treated chronic gout.

Questions answered

• What patient shares do key therapies and brands garner by line of therapy in newly diagnosed chronic gout patients? What are the quarterly trends in prescribing among recently treated and newly diagnosed chronic gout patients?
• How has pegloticase been integrated into the treatment algorithm, and what is its source of business?
• What percentage of chronic gout patients receive drug therapy within 365 of diagnosis, and how quickly? What percentage of patients progress to later lines of therapy within 365 of diagnosis?
• What percentage of chronic gout patients are treated with monotherapy vs. combination therapy? What are the most used combinations?
• What are the product-level compliance and persistency rates among drug-treated patients?

Product description

Treatment Algorithms: Claims Data Analysis provides detailed, quantitative analysis of the treatment journey and brand usage across lines of therapy and overall using real-world, patient-level claims data, enabling you to:

• Understand patient flow between lines of therapy.
• Evaluate your brand share against competitors.
• Accurately assess your source of business.
• Quantify opportunities at different stages of the treatment algorithm.

Product enhancement

Treatment Algorithms: Claims Data Analysis leverages Clarivate’s proprietary Real-World Data, which brings larger patient samples, broader payer coverage, and faster availability for more robust and timely analyses. Additionally, we include new patient demographic analyses: age, gender, ethnicity, and region.