Systemic Lupus Erythematosus – Current Treatment – Treatment Algorithms: Claims Data Analysis – Systemic Lupus Erythematosus (US)
Systemic lupus erythematosus (SLE) is an autoimmune disease that affects multiple organ systems of the body. Symptoms range from general malaise to serious renal and CNS manifestations. Hydroxychloroquine, corticosteroids, and conventional immunosuppressants are the main treatments for SLE. Unfortunately, many patients with SLE fail to respond to these therapies and/or experience significant adverse events. Clinicians may then prescribe other available agents, such as the biologics Benlysta (GSK), Saphnelo (AstraZeneca), Gazyva (Roche), Rituxan (Roche; off-label), and Orencia (BMS; off-label) or the novel calcineurin inhibitor Lupkynis (Aurinia). This content provides insight into drug use and market trends in the SLE space.
Questions answered
- What patient shares do key therapies and brands garner by line of therapy in newly diagnosed SLE patients? What are the quarterly trends in prescribing among recently treated and newly diagnosed SLE patients?
- How have Saphnelo and Lupkynis been integrated into the treatment algorithm, and what are their sources of business?
- What percentage of SLE patients receive drug therapy within one year of diagnosis, and how quickly? What percentage of patients progress to later lines of therapy within one year of diagnosis
- What percentage of SLE patients are treated with monotherapy vs. combination therapy? What are the most commonly used combinations?
- What are the product-level compliance and persistency rates among drug-treated patients?
Markets covered: United States
Key companies: GSK, AstraZeneca, Aurinia, Roche
Key drugs: Benlysta, Rituxan, Saphnelo, Lupkynis, Gazyva, mycophenolate mofetil, hydroxy-chloroquine
Product description
Treatment Algorithms: Claims Data Analysis provides detailed, quantitative analysis of the treatment journey and brand usage across lines of therapy and overall, using real-world, patient-level claims data, enabling you to:
- Understand patient flow between lines of therapy.
- Evaluate your brand share against competitors.
- Accurately assess your source of business.
- Quantify opportunities at different stages of the treatment algorithm.
Product enhancement
Treatment Algorithms: Claims Data Analysis leverages Clarivate’s proprietary Real-World Data, which brings larger patient samples, broader payer coverage, and faster availability for more robust and timely analyses. Additionally, we include new patient demographic analyses: age, gender, ethnicity, and region.
Key feature
Dashboard featuring interactive visuals, easy navigation, and expanded analyses
