Product logins

Find logins to all Clarivate products below.


Colorectal Cancer | Current Treatment: Physician Insights | US | 2019

Market Outlook

Chemotherapies and targeted agents continue to dominate the treatment of colorectal cancer, although targeted agents (e.g., Avastin, Erbitux, Vectibix) are currently confined to the metastatic setting. The FDA approvals of the PD-1 inhibitors Keytruda (Merck & Co.) and Opdivo (Bristol-Myers Squibb) in 2017 and of Opdivo plus Yervoy in 2018 for microsatellite instability-high (MSI-H) or DNA mismatch repair-deficient (dMMR) metastatic colorectal cancer herald the entry of immunotherapy treatments to this biomarker-defined patient population.

Questions Answered

  • What is the uptake of Keytruda and Opdivo in the previously treated MSI-H/dMMR metastatic colorectal cancer segment in the United States, and what are the main obstacles to prescribing these immunotherapies?
  • What is the patient share of key therapies used to treat RASwild-type and RAS-mutant metastatic colorectal cancer?
  • What drivers and obstacles influence treatment decisions in the metastatic setting for select targeted therapies?
  • How do drug-treatment rates vary between key colorectal cancer patient segments, according to biomarker status and line of therapy?

Product Description

Current Treatment: Physician Insights provides physician insights on treatment dynamics, prescribing behavior, and drivers of brand use so that marketers can create specific messaging around these treatment dynamics to more effectively increase or defend their market position.

Geographies: United States

Primary Research: Survey of 100 medical oncologists in the United States

Key Drugs Covered: Avastin, Erbitux, Vectibix, Lonsurf, Keytruda, Opdivo, Zaltrap, Cyramza, Stivarga, Yervoy

Related Market Assessment Reports

Report
Asthma – Unmet Need – Unmet Need – Severe Asthma (US/EU)
Several effective anti-inflammatory agents and bronchodilators are available for controlling patients’ mild or moderate asthma. However, despite the availability of LAMAs (e.g., Boehringer…
Report
Systemic Lupus Erythematosus – Current Treatment – Treatment Algorithms: Claims Data Analysis – Systemic Lupus Erythematosus (US)
Systemic lupus erythematosus (SLE) is an autoimmune disease that affects multiple organ systems of the body. Symptoms range from general malaise to serious renal and CNS manifestations…
Report
Chronic Kidney Disease – Current Treatment – Treatment Algorithms: Claims Data Analysis – Chronic Kidney Disease (US)
Chronic kidney disease (CKD) is caused by structural or functional abnormalities in the kidney that impair its ability to filter blood. The CKD drug market primarily comprises therapies, which are…
Report
Multiple Sclerosis – Current Treatment – Treatment Algorithms: Claims Data Analysis – Multiple Sclerosis (US)
The multiple sclerosis (MS) therapy market comprises more than 20 immunomodulatory disease-modifying therapies (DMTs), and more are in the pipeline. A variety of drug classes each hold a niche…
Report
Asthma – Access & Reimbursement – Access & Reimbursement – Asthma (US)
The dynamics within the LABA/ICS FDC, LAMA, LABA/LAMA/ICS FDC, and biological drug classes will continue to shape the U.S. asthma market. The dominance of branded LABA/ICS FDCs (e.g., GSK’s…