Product logins

Find logins to all Clarivate products below.


Osteoarthritic Pain | Current Treatment: Physician Insights | US | 2017

Market Outlook

Osteoarthritis (OA) pain is an extremely prevalent type of chronic pain, affecting more than 30 million individuals in the United States, and is the second-largest segment of the overall chronic pain market. Treatment of OA pain is dominated by cost-effective generic treatments, in addition to costly abuse-deterrent reformulations of opioid analgesics and new combinations of existing analgesics that attempt to mitigate side effects; no truly novel or mechanism-based therapies are currently available. The key drug classes prescribed to treat OA pain, nonsteroidal anti-inflammatory drugs (NSAIDs) and opioid analgesics, are associated with a host of side effects including gastrointestinal, cardiovascular, and/or abuse risks. As such, treatment of this indication can be challenging for physicians because existing therapies are frequently inadequate in achieving long-term analgesia in many patients.

Questions Answered

  • How is OA pain being treated in the United States today, and what are the drivers and constraints influencing physicians’ treatment decisions?
  • What impact have the recent launches of new analgesics such as Iroko’s Vivlodex and Purdue’s Hysingla ER had on physician prescribing behavior for OA pain?
  • What factors drive switching between or discontinuation of select analgesics (e.g., Depomed’s Nucynta ER, Horizon’s Vimovo, Pfizer’s Embeda)?
  • How does patient risk for abuse/history of abuse influence physicians’ prescribing of opioid analgesics for OA pain?

Product Description

Current Treatment: Physician Insights provides physician insights on treatment paths, prescribing behaviors, and the factors and perceptions driving brand usage so you can create specific messaging around these treatment dynamics in order to more effectively increase or defend your market position.

Related Market Assessment Reports

Report
Hemophilia A – Current Treatment – Current Treatment: Physician Insights – Hemophilia A with Inhibitors (US)
Development of neutralizing antibodies against factor VIII replacement is the most significant clinical complication in hemophilia A, necessitating specialized and often high-cost management…
Report
Major Depressive Disorder (DSM-V) – Access & Reimbursement – Access & Reimbursement – Major Depressive Disorder (US)
Numerous drugs from multiple drug classes are used as monotherapies and/or adjunctive therapies to treat major depressive disorder (MDD). Early-line treatment is dominated by generically available…
Report
Malignant Melanoma – Unmet Need – Unmet Need – BRAF Wild-Type, Unresectable or Metastatic Malignant Melanoma (US/EU)
Treatment for BRAF wild-type unresectable or metastatic melanoma has been largely shaped by the successive approvals of immune checkpoint inhibitors. Anti-PD-1 agents such as Keytruda (Merck & Co…
Report
Systemic Lupus Erythematosus | Unmet Need | Moderate to Severe Systemic Lupus Erythematosus | US/EU | 2024
Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect different organ systems of the body and manifest in a wide range of clinical symptoms, from general fatigue to serious…
Report
Systemic Lupus Erythematosus – Unmet Need – Unmet Need – Moderate to Severe Systemic Lupus Erythematosus (US/EU)
Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect different organ systems of the body and manifest in a wide range of clinical symptoms, from general fatigue to serious…