Product logins

Find logins to all Clarivate products below.


MARKET OUTLOOK

In the past decade, AbbVie’s Humira and Amgen’s Enbrel tumor necrosis factor-alpha (TNF-α) inhibitors and Janssen’s interleukin (IL)-12/23 inhibitor Stelara have been leading the U.S. psoriasis biologics market. However, the recent wave of U.S. approvals for novel psoriasis agents—including Celgene’s Otezla, three IL-17 inhibitors, and two IL-23 inhibitors—is altering the market landscape. The oral agent Otezla has been successfully carving out a space in biologics-naive patients. The more-effective biologics, Novartis’s Cosentyx and Eli Lilly’s TaltzIL-17 inhibitors, are threatening the first-line dominance of TNF-α inhibitors, and Janssen’s IL-23 inhibitor Tremfya is likely to follow. With the recent entry of biosimilars and another IL-23 inhibitor in late-phase development, marketers of psoriasis therapies will learn how they can best overcome the formulary and uptake challenges facing current and emerging therapies in this increasingly competitive market.

QUESTIONS ANSWERED

  • What are the current patient share leaders among psoriasis biologics/Otezla, and which psoriasis agents do physicians and payers perceive as performing best on specific clinical and market access factors?
  • How do payers cover/anticipate covering biosimilar versions of infliximab (Pfizer’s Inflectra, Merck’s Renflexis) and adalimumab (Amgen’s Amgevita), and what are physicians’ expected prescribing behaviors of biosimilars?
  • What are physician perceptions of emerging biologics, such as risankizumab, and how do payers anticipate covering these novel agents? How are recent entrants to the market faring in terms of payer coverage and restrictions?
  • What pharmacoeconomic models and data do payers value for examining the cost and efficacy impact of novel psoriasis agents?

PRODUCT DESCRIPTION

Access & Reimbursement provides in-depth insight regarding the impact of payer policy on physician prescribing behavior so you can build your market access strategy and optimize your brand positioning.

Related Market Assessment Reports

Report
Atopic Dermatitis / Atopic Eczema – Geographic Focus: China – Atopic Dermatitis – China In-Depth (China)
China’s atopic dermatitis (AD) market remains grounded in established topical and systemic therapies, although limitations in longterm disease control leave a sizable unmet need among…
Report
Dry and Wet Age-Related Macular Degeneration – Access & Reimbursement – Access & Reimbursement – Age-Related Macular Degeneration (US)
The U.S. wet AMD market is led by intravitreal therapies such as Eylea, Eylea HD, and Vabysmo, alongside the continued off-label use of compounded Avastin, driven by cost considerations. In…
Report
Psoriatic Arthritis – Current Treatment – Treatment Algorithms: Claims Data Analysis – Psoriatic Arthritis (US)
Treatment of psoriatic arthritis (PsA) typically begins with conventional disease-modifying antirheumatic drugs (DMARDs), such as methotrexate, and progresses to more potent biologics and/or…
Report
Peripheral Arterial Disease – Current Treatment – Treatment Algorithms: Claims Data Analysis – Peripheral Artery Disease (US)
Peripheral artery disease (PAD) is a subtype of atherosclerotic cardiovascular disease affecting the arteries of the lower extremities and is associated with reduced walking capacity, claudication…
Report
Irritable Bowel Syndrome – Current Treatment – Treatment Algorithms: Claims Data Analysis – IBS-Constipation (including IBS without Diarrhea) (US)
Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder characterized by altered bowel motility, stool consistency, and frequency, and is classified into constipation-predominant,…