Product logins

Find logins to all Clarivate products below.


Ovarian Cancer | Current Treatment: Physician Insights | US | 2019

Chemotherapy remains the standard of care for the treatment of ovarian cancer, but new classes of drugs such as angiogenesis inhibitors and, more recently, PARP inhibitors have entered the therapeutic landscape for this indication. The regulatory approvals of targeted therapies, such as Roche / Genentech’s Avastin, AstraZeneca’s Lynparza, Clovis Oncology’s Rubraca, and Tesaro’s Zejula, have changed physicians’ prescribing habits and created new dynamics in treatment sequencing. In December 2018, Lynparza became the first PARP inhibitor to gain FDA approval as a first-line maintenance therapy for ovarian cancer with BRCA mutations.

Questions Answered

  • What is the uptake of Avastin and Lynparza as maintenance therapies for first-line advanced-stage ovarian cancer according to surveyed oncologists?
  • What is the patient share of key therapies for advanced-stage (first- to fourth-line) ovarian cancer?
  • What are the key drivers and obstacles determining current prescribing of Avastin and PARP inhibitors for advanced-stage ovarian cancer?
  • How do drug-treatment rates vary across key ovarian cancer patient populations, according to stage of disease and line of therapy?

Product Description

Current Treatment: Physician Insights provides physician insights on treatment dynamics, prescribing behavior, and drivers of brand use so that marketers can create specific messaging around these treatment dynamics to more effectively increase or defend their market position.

Markets covered: United States

Primary research: Survey of 100 medical oncologists in the United States fielded in March 2019.

Key drugs covered: Avastin, Lynparza, Zejula, Rubraca

Related Market Assessment Reports

Report
Axial Spondyloarthritis – Current Treatment – Treatment Algorithms: Claims Data Analysis – Ankylosing Spondylitis (US)
Ankylosing spondylitis (AS) is a chronic inflammatory disease that primarily affects the sacroiliac joints and the axial skeleton, leading to persistent back pain and stiffness. The main treatment…
Report
Insomnia – Current Treatment – Current Treatment: Physician Insights – Insomnia (EU5)
Insomnia is a common sleep disorder characterized by difficulty initiating or maintaining sleep, leading to impaired daytime functioning. Its management is highly personalized, with clinicians…
Report
Alopecia – Current Treatment – Treatment Algorithms: Claims Data Analysis – Alopecia Areata (US)
Alopecia areata (AA) is an autoimmune condition in which the immune-mediated damage to hair follicles results in patchy or extensive hair loss. AA treatment is evolving rapidly as dermatologists…
Report
Immune Thrombocytopenic Purpura – Current treatment – Treatment Algorithms: Claims Data Analysis – Immune Thrombocytopenic Purpura (US)
Immune thrombocytopenic purpura (ITP) is an autoimmune disorder characterized by a low platelet count, resulting in an increased risk of bleeding. Current therapies for ITP can be largely divided…
Report
Myasthenia Gravis – Geography Focus: China – China In-Depth: Myasthenia Gravis
China’s myasthenia gravis (MG) market is transitioning from long-standing symptomatic regimens toward a more structured mix of targeted therapies that increasingly shape treatment pathways…