Product logins

Find logins to all Clarivate products below.


Prostate Cancer | Current Treatment: Physician Insights | US | 2019

Hormonal therapies have dominated the treatment of prostate cancer for the past decade. Zytiga (Janssen, generics) and Xtandi (Medivation / Astellas Pharma), initially approved for metastatic castrate-resistant prostate cancer (mCRPC), account for a sizeable market share in this setting. However, following their label expansions, these agents are also quickly becoming standards of care for newly diagnosed metastatic hormone-sensitive prostate cancer (mHSPC). Xofigo (Bayer HealthCare) and Jevtana (Sanofi) are nonhormonal treatments for mCRPC, particularly in later lines. The penetration of Zytiga (abiraterone), Xtandi, Erleada, and nonhormonal agents (e.g., docetaxel) into other patient populations (e.g., newly diagnosed mHSPC, nonmetastatic CRPC [nmCRPC]) will be key market drivers. This report examines surveyed medical oncologists’ and urologists’ current prescribing practices for prostate cancer in the United States and analyzes the key drivers influencing their treatment decisions.

Questions Answered

  • What are the drug-treatment rates across clinically and commercially relevant prostate cancer patient populations?
  • How much uptake have Xtandi and Erleada experienced in the nmCRPC setting to date, according to U.S. medical oncologists and urologists?
  • What are the patient shares of key therapies used to treat mCRPC, mHSPC, and nmCRPC across all lines of therapy?
  • What are the main drivers of, and obstacles to, the prescribing of current therapies for mCRPC, mHSPC, and nmCRPC?

Product Description

Current Treatment: Physician Insights provides physician insights on treatment dynamics, prescribing behavior, and drivers of brand use so that marketers can create specific messaging around these treatment dynamics to more effectively increase or defend their market position.

Markets covered: United States

Primary research: Survey of 102 medical oncologists and urologists (51 of each specialty) in the United States fielded in April-May 2019.

Key drugs covered: Zytiga / abiraterone acetate, Xtandi, Erleada, Yonsa, Provenge, Xofigo, Jevtana

Related Market Assessment Reports

Report
Asthma – Access & Reimbursement – Access & Reimbursement – Asthma (US)
The dynamics within the LABA/ICS FDC, LAMA, LABA/LAMA/ICS FDC, and biological drug classes will continue to shape the U.S. asthma market. The dominance of branded LABA/ICS FDCs (e.g., GSK’s…
Report
Systemic Lupus Erythematosus – Access & Reimbursement – Access & Reimbursement – Systemic Lupus Erythematosus (US)
The U.S. systemic lupus erythematosus (SLE) therapy market is largely genericized and off-label. With the exception of GSK’s Benlysta, the firstagents approved for the indication in almost 60…
Report
Heart Failure – Current Treatment – Treatment Algorithms: Claims Data Analysis – Heart Failure with Reduced Ejection Fraction (US)
Heart failure with reduced ejection fraction (HFrEF) occurs when the left ventricular ejection fraction (LVEF) is 40% or less. Drug treatment for HFrEF is well established and supported by…
Report
Heart Failure – Current Treatment – Treatment Algorithms: Claims Data Analysis – Heart Failure with Preserved Ejection Fraction (US)
Heart failure with preserved ejection fraction (HFpEF) occurs when the left ventricular ejection fraction (LVEF) is 50% or more. Even though physicians’ understanding of the disease’s…
Report
Membranous Nephropathy – Landscape & Forecast – Disease Landscape & Forecast (G7)
Primary membranous nephropathy (pMN), the most common type of MN, is a rare autoantibody-mediated autoimmune kidney disease. Although it is one of the leading causes of nephrotic syndrome in…