Product logins

Find logins to all Clarivate products below.


Hemophilia A | Treatment Algorithms: Claims Data Analysis | US | 2024

Hemophilia A is a monogenic X-linked recessive bleeding disorder caused by a deficiency in factor VIII. Currently, FVIII recombinant therapies, bypass agents, Hemlibra, and vasopressin receptor agonists are used in the management of hemophilia A. Hemlibra has been a transformative treatment for patients with hemophilia A by offering improved treatment outcomes, reduced dosing burden, and convenient subcutaneous administration. In this report, we closely examine how key current therapies are being used in the treatment of newly diagnosed and recently treated hemophilia A patients in the United States.

Questions answered

  • What patient shares do key therapies and brands garner by line of therapy in newly diagnosed hemophilia A patients? What are the quarterly trends in prescribing among recently treated and newly diagnosed hemophilia A patients?
  • How has Hemlibra been integrated into the treatment algorithm, and what is its source of business?
  • What percentage of hemophilia A patients receive drug therapy within one year of diagnosis, and how quickly? What percentage of patients progress to later lines of therapy within two years of diagnosis?
  • What percentage of hemophilia A patients are treated with monotherapy versus combination therapy? What are the most commonly used combinations?
  • What are the product-level compliance and persistency rates among drug-treated patients?

Markets covered: United States

Key companies: Baxter HealthCare, Novo Nordisk, BioMarin, Takeda, Sanofi, Genentech 

Key drugs: Hemlibra, Roctavian, Altuviiio, Eloctate, Esperoct, Adynovate, Jivi, SHL FVIIIs 

Product description

Treatment Algorithms: Claims Data Analysis provides detailed, quantitative analysis of the treatment journey and brand usage across lines of therapy and overall using real-world, patient-level claims data so that marketers can accurately assess their source of business, benchmark usage against competitors, and quantify areas of opportunity for their marketed or emerging brand.

Key feature

Dashboard featuring interactive visuals, easy navigation, and expanded analyses

Related Market Assessment Reports

Report
Venous Thromboembolism – Current Treatment – Treatment Algorithms: Claims Data Analysis – Venous Thromboembolism (US)
Venous thromboembolism (VTE) is the obstruction of a vein caused by a thrombus, described as deep vein thrombosis (DVT) or pulmonary embolism (PE), depending on the vein affected. Anticoagulants…
Report
Asthma – Current Treatment – Treatment Algorithms: Claims Data Analysis – Adult Asthma (US)
Two types of pharmacotherapies are used in parallel to treat adult asthma: rescue drugs and maintenance therapies. Rescue drugs are inhaled therapies that treat the acute symptoms of asthma via…
Report
Attention-Deficit-Hyperactivity Disorder – Current Treatment – Treatment Algorithms: Claims Data Analysis – Adult ADHD (US)
Attention-deficit / hyperactivity disorder (ADHD), a common childhood neurodevelopmental condition that can persist into adulthood, affects about 6% of U.S. adults, or approximately 15.5 million…
Report
Cystic Fibrosis – Unmet Need – Unmet Need – Cystic Fibrosis (US EU)
Cystic fibrosis (CF) is a genetic disease associated with more than 2,000 mutations identified in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. These mutations cause aberrant…
Report
Hyperkalemia – Current Treatment – Treatment Algorithms: Claims Data Analysis – Hyperkalemia (US)
Hyperkalemia is defined as a serum potassium level above 5.0 mEq/L. This report covers the management of chronic hyperkalemia through diuretic therapy, correcting metabolic acidosis when present,…