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Cracking the code: Generating and validating hypotheses for target identification
Selecting the right target is the most important investment decision in drug discovery; over 40% of clinical trial failures are due to no clear link being made between target and disease.
Clarivate discovery and preclinical solutions empower R&D teams to make faster, more informed decisions to increase the chances of successfully translating research findings into human applications and achieving success in clinical trials.
This case study shows how researchers can use Clarivate solutions to generate and validate hypotheses for target identification, thereby saving time and money before proceeding to further lab-based validation:
- Define hypotheses for putative targets by uncovering the molecular mechanisms underlying various biological phenomena.
- Further evaluate these hypotheses with additional evidence of the link between the target and the disease.
- Develop a comprehensive understanding of what is known about these targets, before embarking on lab experiments.
