Product logins

Find logins to all Clarivate products below.


Non-Small-Cell Lung Cancer | Current Treatment: Physician Insights | US | May 2025

Immune checkpoint inhibitors continue to dominate the treatment of non-small-cell lung cancer (NSCLC), while biomarker-based approaches are driving increasing patient segmentation. In 2024, Imfinzi and Alecensa gained label expansions into the resectable early-stage NSCLC space. Additionally, Opdivo plus chemotherapy gained FDA approval for perioperative (neoadjuvant then adjuvant) use in this setting. The metastatic setting also saw new entrants to the space, with the approval of new biomarker-targeted agents: Bizengri for NRG1-mutated NSCLC, and Ensacove for NSCLC with ALK mutations. Additionally, Tecentriq Hybreza, a subcutaneous formulation of Tecentriq, was also approved in all adult indications approved for Tecentriq, including NSCLC. These approvals, against the backdrop of numerous existing agents in the NSCLC space, provide medical oncologists with an ever-increasing array of treatment options.

Questions answered

  • What are the treatment rates for NSCLC in the various settings and lines of therapy?
  • What are the rates of testing for different biomarkers, and what is the uptake of key biomarker-driven therapies?
  • How are new therapy entrants to the NSCLC market performing relative to existing therapies?
  • What do surveyed physicians consider the main drivers of and key obstacles to the uptake of select therapies?

Product description

Through survey data from U.S. physicians, Current Treatment: Physician Insights offers in-depth analyses of the reasons behind treatment dynamics, prescribing behavior, and brand preference, enabling you to:

  • Understand the treatment landscape for a disease and how physicians make prescribing decisions.
  • Evaluate the drivers and obstacles that influence treatment selection.
  • Analyze your brand’s performance from the physician perspective to enhance or defend your competitive position.

Primary research: Survey of 102 U.S. medical oncologists in the United States fielded during February 24 to March 7, 2025.

Key drugs covered: Alecensa, Enhertu, Gavreto, Imfinzi, Imjudo, Keytruda, Krazati, Libtayo, Lumakras, Opdivo, Retevmo, Rybrevant, Tabrecta, Tagrisso, Tecentriq, Tecentriq Hybreza, Tepmetko, Yervoy.

Related Market Assessment Reports

Report
Hemophilia A – Current Treatment – Current Treatment: Physician Insights – Hemophilia A with Inhibitors (US)
Development of neutralizing antibodies against factor VIII replacement is the most significant clinical complication in hemophilia A, necessitating specialized and often high-cost management…
Report
Major Depressive Disorder (DSM-V) – Access & Reimbursement – Access & Reimbursement – Major Depressive Disorder (US)
Numerous drugs from multiple drug classes are used as monotherapies and/or adjunctive therapies to treat major depressive disorder (MDD). Early-line treatment is dominated by generically available…
Report
Malignant Melanoma – Unmet Need – Unmet Need – BRAF Wild-Type, Unresectable or Metastatic Malignant Melanoma (US/EU)
Treatment for BRAF wild-type unresectable or metastatic melanoma has been largely shaped by the successive approvals of immune checkpoint inhibitors. Anti-PD-1 agents such as Keytruda (Merck & Co…
Report
Systemic Lupus Erythematosus | Unmet Need | Moderate to Severe Systemic Lupus Erythematosus | US/EU | 2024
Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect different organ systems of the body and manifest in a wide range of clinical symptoms, from general fatigue to serious…
Report
Systemic Lupus Erythematosus – Unmet Need – Unmet Need – Moderate to Severe Systemic Lupus Erythematosus (US/EU)
Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect different organ systems of the body and manifest in a wide range of clinical symptoms, from general fatigue to serious…