Chronic Myelogenous Leukemia: Prescribing Decisions and Payer Landscape in a Crowded and Dynamic Market | Physician & Payer Forum | EU5 | 2014
Tyrosine kinase inhibitors (TKIs) have revolutionized the management of chronic myelogenous leukemia (CML) over the last decade. However, as 2013-approved second-generation TKIs Bosulif (Pfizer’s bosutinib) and Iclusig (Ariad Pharmaceuticals’ ponatinib) join Glivec (Novartis’s imatinib), Sprycel (Bristol-Myers Squibb’s dasatinib), and Tasigna (Novartis’s nilotinib), treatment decisions are becoming increasingly challenging—especially in later lines of CML therapy—with each TKI agent offering a unique blend of benefits and risks, on top of a premium price tag.
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