Product logins

Find logins to all Clarivate products below.


Ovarian Cancer | Current Treatment: Physician Insights | US | 2019

Chemotherapy remains the standard of care for the treatment of ovarian cancer, but new classes of drugs such as angiogenesis inhibitors and, more recently, PARP inhibitors have entered the therapeutic landscape for this indication. The regulatory approvals of targeted therapies, such as Roche / Genentech’s Avastin, AstraZeneca’s Lynparza, Clovis Oncology’s Rubraca, and Tesaro’s Zejula, have changed physicians’ prescribing habits and created new dynamics in treatment sequencing. In December 2018, Lynparza became the first PARP inhibitor to gain FDA approval as a first-line maintenance therapy for ovarian cancer with BRCA mutations.

Questions Answered

  • What is the uptake of Avastin and Lynparza as maintenance therapies for first-line advanced-stage ovarian cancer according to surveyed oncologists?
  • What is the patient share of key therapies for advanced-stage (first- to fourth-line) ovarian cancer?
  • What are the key drivers and obstacles determining current prescribing of Avastin and PARP inhibitors for advanced-stage ovarian cancer?
  • How do drug-treatment rates vary across key ovarian cancer patient populations, according to stage of disease and line of therapy?

Product Description

Current Treatment: Physician Insights provides physician insights on treatment dynamics, prescribing behavior, and drivers of brand use so that marketers can create specific messaging around these treatment dynamics to more effectively increase or defend their market position.

Markets covered: United States

Primary research: Survey of 100 medical oncologists in the United States fielded in March 2019.

Key drugs covered: Avastin, Lynparza, Zejula, Rubraca

Related Market Assessment Reports

Report
Heart Failure – Current Treatment – Treatment Algorithms: Claims Data Analysis – Heart Failure with Reduced Ejection Fraction (US)
Heart failure with reduced ejection fraction (HFrEF) occurs when the left ventricular ejection fraction (LVEF) is 40% or less. Drug treatment for HFrEF is well established and supported by…
Report
Heart Failure – Current Treatment – Treatment Algorithms: Claims Data Analysis – Heart Failure with Preserved Ejection Fraction (US)
Heart failure with preserved ejection fraction (HFpEF) occurs when the left ventricular ejection fraction (LVEF) is 50% or more. Even though physicians’ understanding of the disease’s…
Report
Membranous Nephropathy – Landscape & Forecast – Disease Landscape & Forecast (G7)
Primary membranous nephropathy (pMN), the most common type of MN, is a rare autoantibody-mediated autoimmune kidney disease. Although it is one of the leading causes of nephrotic syndrome in…
Report
Irritable Bowel Syndrome – Current Treatment – Treatment Algorithms – Claims Data Analysis – IBS-Diarrhea (US)
Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder characterized by alterations in motility, stool consistency and frequency, and urgency. The disorder is grouped into three…
Report
Migraine – Access & Reimbursement – Access & Reimbursement – Migraine Prophylaxis (US)
Preventive migraine care in the United States continues to evolve. Since 2018, CGRPtargeting mAbs (Aimovig, Emgality, Ajovy, Vyepti) and oral gepants (Nurtec ODT, Qulipta) have become established…