Product logins

Find logins to all Clarivate products below.


Hepatitis C Virus and Government Programs | Physician & Payer Forum | US | 2015

The Impact of Premium-Priced Market Entrants on MCO-Run Medicare and Medicaid Plans
The groundbreaking therapies for the Hepatitis C virus (HCV) promise high cure rates for millions of Americans afflicted with chronic infection. But these drugs have also strained the public insurance sector, prompting concern among managed care organizations (MCOs) that the high costs of the new direct-acting antivirals (DAAs) will endanger the financial viability of their Medicaid and Medicare Advantage plans. Daunted by the $84,000 price tag of Gilead’s Sovaldi (sofosbuvir) when the first interferon-free therapy hit the market in 2014, many MCOs have been responding with limitations on coverage, forcing prescribers to navigate long prior authorization requirements. The introduction of new DAAs, including Gilead’s Harvoni (sofosbuvir/ledipasvir) and AbbVie’s Viekira Pak ombitasvir/paritaprevir/ritonavir + dasabuvir), has led to significant price relief through competitive contracting. Nevertheless, HCV drug costs, combined with the magnitude of the demand, continue to pose a financial concern to MCOs, particularly in light of the wave of expensive specialty drugs emerging from the pipeline.

Related Market Assessment Reports

Report
Psoriatic Arthritis – Current Treatment – Treatment Algorithms: Claims Data Analysis – Psoriatic Arthritis (US)
Treatment of psoriatic arthritis (PsA) typically begins with conventional DMARDs, such as methotrexate, and progresses to more-potent biologics and/or targeted oral therapies as needed. The U.S…
Report
Atopic Dermatitis / Atopic Eczema – Access & Reimbursement – Access & Reimbursement – Atopic Dermatitis (US)
The treatment landscape for AD in the United States is evolving rapidly. Since 2017, the FDA has approved multiple agents, including systemic and topical JAK inhibitors, nonsteroidal topical…
Report
Renal Anemia – Current Treatment – Treatment Algorithms: Claims Data Analysis – Renal Anemia (US)
Renal anemia is a common complication of chronic kidney disease (CKD). When kidneys are diseased or impaired, they fail to generate enough EPO, causing renal anemia. The primary goal of renal…
Report
Painful Diabetic Neuropathy – Current Treatment – Treatment Algorithms: Claims Data Analysis – Painful Diabetic Neuropathy (US)
Painful diabetic neuropathy (PDN) is characterized by numbness, tingling, and burning, sharp, shooting, or other painful sensations, commonly in the feet, legs, and/or hands. PDN is managed with…
Report
Systemic Lupus Erythematosus – Landscape & Forecast – Disease Landscape & Forecast (G7)
Systemic lupus erythematosus (SLE) is a complex autoimmune disease that can affect nearly any organ or system in the body. As a result, its course, manifestations, and treatment can be highly…