Atopic Dermatitis | Niche and Rare Pharmacor | G7 | 2015
Atopic dermatitis (AD), also known as (atopic) eczema, is a chronic, relapsing inflammatory skin disease marked by severe pruritus and skin irritation which can have a strong negative impact on patients’ quality of life, in particular in moderate and severe patients. Standard treatments for AD attempt to reduce inflammation and pruritus with combinations of emollients, topical corticosteroids, and topical immunomodulators. Additionally, systemic immunomodulators, and in some cases UV phototherapy, are used to treat AD. Treatment with topical therapies and anti-inflammatory agents is often successful; however, more-effective therapies for treatment-refractory AD represent an area of tremendous unmet need.
