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Prostate Cancer (First-Line [Chemotherapy-Naive] Metastatic Castrate-Resistant) | Decision Base | US/EU | 2014

As Abiraterone and Enzalutamide Gain Traction in the Market, What Key Attributes Do Oncologists and Payers Say Will Differentiate Emerging Therapies?

The first-line (chemotherapy-naive) metastatic castrate-resistant prostate cancer (mCRPC) market is becoming increasingly crowded. In recent years, several new, high-priced therapies have been approved for use in this patient population, making this lucrative market more dynamic and competitive. The launch of these agents has significantly altered the treatment algorithm and improved the outlook for patients; nevertheless, our research indicates that significant clinical and commercial opportunity remains for therapies that can further extend overall survival. Several therapies are in late-stage development for first-line (chemotherapy-naive) mCRPC, though we do not we anticipate that all of these agents will be approved for this indication.

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