Product logins

Find logins to all Clarivate products below.


Schizophrenia | Access and Reimbursement | US | 2017

Market Outlook

Atypical antipsychotics—the cornerstone of schizophrenia treatment—are available as oral and long-acting depot formulations in the United States. Many of the oral atypical antipsychotic therapies used to treat the symptoms of schizophrenia are generically available, potentially creating barriers to access for branded oral agents (e.g., Sunovion’s Latuda, Otsuka/Lundbeck’s Rexulti, Allergan’s Vraylar). Newer depot formulations of atypical antipsychotics (e.g., Alkermes’s Aristada, Janssen’s Invega Trinza) offer the possibility of better patient compliance, although access to these therapies also may be restricted due to their high cost relative to other agents. With a wide variety of antipsychotic therapy options available, novel oral schizophrenia therapies will be entering a crowded and highly genericized market and may face reimbursement difficulties.

Questions Answered

  • How do payer policies affect the prescribing of branded oral atypical antipsychotics (e.g., Latuda, Rexulti, Vraylar) and depot atypical antipsychotics (e.g., Otsuka/Lundbeck’s Abilify Maintena, Janssen’s Risperdal Consta) in this genericized market?
  • What do payers report as the coverage status of branded oral and depot atypical antipsychotics on Medicaid and commercial plans? Is automatic generic substitution employed for oral therapies that are generically available?
  • What are the preferred pharmacoeconomic models for payers when evaluating new schizophrenia therapies, and what types of pharmacoeconomic data do they find most compelling?
  • How do payers anticipate including emerging oral schizophrenia therapies on formularies at various price points, and how do psychiatrists expect to incorporate them in the treatment of schizophrenia patients?

Product Description

Access & Reimbursement: Provides in-depth insight regarding the impact of payer policy on physician prescribing behavior so you can build your market access strategy and optimize your brand positioning.

Related Market Assessment Reports

Report
Bipolar Disorder – Current Treatment – Treatment Algorithms: Claims Data Analysis – Bipolar Disorder (US)
Bipolar disorder (BPD) is a chronic condition characterized by recurrent episodes of aberrant mood, with patients experiencing manic, depressive, or mixed symptoms between periods of stable mood…
Report
Type 1 Diabetes – Current Treatment – Treatment Algorithms: Claims Data Analysis – Type 1 Diabetes (US)
Intensive insulin regimens have proven effective in delaying the progression of complications associated with untreated or poorly treated type 1 diabetes (T1D). Thus, insulins remain the…
Report
Rheumatoid Arthritis – Current Treatment – Treatment Algorithms: Claims Data Analysis – Rheumatoid Arthritis (US)
The treatment of rheumatoid arthritis (RA) typically begins with cost-effective conventional DMARDs (cDMARDs) such as methotrexate or hydroxychloroquine. For patients who fail cDMARD treatment or…
Report
Migraine – Current Treatment – Treatment Algorithms: Claims Data Analysis – Acute Migraine (US)
Episodic and chronic migraines are often disabling and reduce patients’ quality of life. Despite triptans’ dominance in the treatment algorithm, many patients respond inadequately, cannot…
Report
Chronic Kidney Disease – Current Treatment – Treatment Algorithms: Claims Data Analysis – Chronic Kidney Disease (US)
Chronic kidney disease (CKD) is caused by structural or functional abnormalities in the kidney that impair its ability to filter blood. The CKD drug market primarily comprises therapies, which are…