Cortellis Pathfinder
The omics data analysis platform built for every scientist
Scale multi-omics insight around research objectives
Cortellis Pathfinder is a research question-driven, multi-omics data analysis platform that helps drug discovery teams turn complex omics data into ranked, biologically interpretable hypotheses. The next evolution of Clarivate’s MetaCore, Cortellis Pathfinder, brings a modern experience to biological pathway analysis and multi-omics data integration.
From raw omics data to clear hypotheses
Empower scientists with self-service analysis
Reproducible, scalable discovery workflows
Turn multi-omics complexity into confident decisions faster
Accelerate target and biomarker discovery
Quickly move from omics data analysis to shortlists of high-value targets and biomarkers, so you can focus experiments on the most promising hypotheses.
Self-serve without coding or installation
Use intuitive, no-code workflows to explore omics data, perform pathway enrichment analysis, and test ideas without relying on scarce bioinformatics support.
Standardize how teams analyze omics data
Apply consistent, reproducible workflows for multi-omics data analysis, reducing variability across projects and strengthening scientific and regulatory confidence.
Reveal hidden biological pathway signals
Combine pathway enrichment analysis and network exploration to uncover subtle biological signals that might be missed by fragmented or manual approaches.
Increase ROI of R&D investments
Improve research speed and quality so more programs advance with clearer biological rationale, increasing the likelihood of clinical and commercial success.
Unify labs and data teams around workflows
Align biologists and bioinformaticians around shared, transparent workflows, cutting rework and enabling faster, more informed decisions on drug and disease mechanisms.
Multi omics data analysis and integration made simple
Research question-driven workflows
Start with scientific goals, not algorithms. Cortellis Pathfinder guides you through end-to-end, question-specific workflows that integrate multi-omics data analysis, pathway enrichment, and network exploration, aligning outputs directly with your research objectives.
No-code, scientist-friendly environment
Interact with complex multi-omics data through an intuitive, no-code solution. Scientists can set up analyses, explore biological pathway analysis results, and generate shareable reports without installing software or writing code, increasing independence and speed.
Expert-curated biological content
Use trusted molecular interactions, with directionality, effect, and mechanism, underpinning your gene pathway analysis and pathway enrichment analysis. This foundation supports reliable multi-omics data integration and helps interpret mechanisms with greater biological confidence.
Reproducible, auditable run history
Capture the run history for each analysis, including inputs, parameters, and outputs. Cortellis Pathfinder makes it easy to revisit, refine, and share workflows, supporting consistent multi-omics data analysis and easing collaboration, review, and compliance needs.
Curated omics data for pathway analysis
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Frequently asked questions
Find answers to common questions about multi omics data analysis software, omics data integration, and pathway enrichment analysis for drug discovery teams.
Cortellis Pathfinder is a research question‑driven, no‑code platform that helps drug discovery scientists and research teams turn complex multi‑omics data into ranked, biologically interpretable hypotheses. It is designed primarily for translational and target discovery scientists, biomarker discovery scientists, and therapeutic area leads, and is also well suited for bioinformaticians, computational biologists, and clinical research scientists who need more consistent, scalable workflows.
No, Cortellis Pathfinder is specifically designed to empower non‑bioinformaticians with an intuitive, no‑code environment—no scripting, local installation, or infrastructure management required. Biologists can upload gene lists or expression tables, select from curated research questions, run analyses, and interpret results themselves, while bioinformaticians benefit from consistent, reproducible workflows that can be standardized across projects.
Cortellis Pathfinder supports the most used types of omics data, including bulk genomics, transcriptomics, proteomics, metabolomics and epigenomics; and multi-omics datasets can be integrated with GWAS and TCGA to prioritize causal genes and pathways associated with traits, diseases, or survival outcomes. You can upload your data in multiple file types, including gene lists, DEG tables, expression matrices and metadata.
Cortellis Pathfinder is the next evolution of Clarivate’s pathway and network analysis capabilities, building on the proven MetaCore foundation while introducing a modern, research question‑driven experience.
Unlike standalone pathway analysis tools that require manual stitching of multiple packages, Cortellis Pathfinder integrates curated molecular interaction content with structured, repeatable workflows so scientists can scale multi‑omics analysis around their scientific questions.
Cortellis Pathfinder is built on Clarivate’s trusted, expert-curated MetaBase content, including over five million curated molecular interactions with directionality, effect, and mechanism. Whereas MetaBase offers seamless data integration into bioinformatics pipelines, omics workflows, AI platforms, and large-scale analytics systems via R, APIs, and SQL, Cortellis Pathfinder empowers researchers’ analytical capabilities without requiring coding.
Yes. Cortellis Pathfinder combines enrichment, network, and pathway‑based approaches to reveal biological processes, key regulators, and relevant gene or protein subnetworks in your data. It then helps you rank targets based on biological relevance, tissue specificity, pathway impact, and disease association, and prioritize biomarkers in the context of survival or response outcomes, as well as potential efficacy or toxicity risks.
