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Cortellis Drug Discovery Intelligence

Accelerate drug development with complete discovery and preclinical intelligence

Make confident R&D decisions and avoid late-stage failures

Advance discovery and preclinical development and avoid late-stage failures with drug intelligence that integrates multi-source scientific data into a single drug discovery platform.

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Benchmark and improve your drug candidates

Compare your drug’s preclinical performance to prior research, with biology, chemistry and pharmacology insights – all in one place.

Identify and prioritize targets and biomarkers

Develop hypotheses for new targets, drugs and biomarkers with intelligence covering the whole drug discovery lifecycle from early-stage development to launch.

Increase the success of your preclinical drug discovery programs

Gain confidence in R&D decisions and avoid late-stage failures using a drug discovery database built by scientists for scientists.

Built for scientists, by scientists

Reliable, enriched data

Access timely and accurate preclinical drug discovery content, curated using a combination of technology and human curation by scientists and subject matter experts.

Granular indexing

Search by drug name, disease areas, chemical structure and more, and drill down to the answers you need with 20+ filters and granular indexed data.

Broad and deep coverage

Unmatched breadth of scientific intelligence, covering global sources and spanning 27+ therapy areas and 6500+ diseases, including rare.

Leverage the most comprehensive drug discovery database available

Make informed go/no-go decisions

Tap into critical R&D data to make confident indication prioritization and drug repurposing decisions, and efficiently move drugs through development. Confirm the link between target and indication and connect all related information with a leading drug discovery platform.

Benchmark drugs’ experimental performance

Understand who is developing drugs like yours and compare experimental performance to better assess your competitors.​ Use previous research to make informed go/no-go decisions regarding your pipeline or design your experiments.​

Understand metabolic pathways

Explore active metabolites and uncover desired pharmacological or off-target activity in humans and animal models. Evaluate competitor drug activity in vitro and in vivo and identify the best assays to test the efficacy of your molecules.

Speed up compound synthesis

Conduct structure searches of your compounds to uncover similar compounds and related synthesis schemes, including intermediates. Benchmark drug candidates based on pharmacology and pharmacokinetics to identify competitive strengths and weaknesses.

Want to learn more about preclinical drug intelligence?

Contact us to schedule a demo of Cortellis Drug Discovery Intelligence

804k+
drugs and biologics
47k+
biomarkers linked to 3m+ biomarker uses
222k
experimental models
53k+
genes and targets
695k+
patent families
1.7m+
target-disease unique relationships

Resources

Identifying crucial biomarker patterns critical for diagnostic accuracy Identifying crucial biomarker patterns critical for diagnostic accuracy
Case study
Identifying crucial biomarker patterns critical for diagnostic accuracy
Clarivate and CLEO diagnostics are making early detection of ovarian cancer a reality
Targeted protein degraders Targeted protein degraders
REPORT
Targeted protein degraders
Hijacking cellular degradation pathways to address "undruggable" targets
Assessing the potential of PROTACs as treatments for Alzheimer's disease Assessing the potential of PROTACs as treatments for Alzheimer's disease
Case study
Assessing the potential of PROTACs as treatments for Alzheimer's disease

PROteolysis TArgeting Chimeras (PROTACs) represent a promising class of drugs designed to degrade disease-causing proteins by leveraging the ubiquitin-proteasome system. The PROTAC field is rapidly evolving, with numerous companies and…

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The research solutions from Clarivate encompass all aspects of data and analytics that give us a commercial advantage.

Richard Allman CEO at Cleo​

For over 10 years, the Cortellis Drug Discovery Intelligence database has proven instrumental in my efforts for understanding competitive landscapes, monitoring current target developments, and exploring disease profiles. With each evolution of the suite and addition of new features, the Cortellis team works hard to onboard their users in order to maximise value in the suite. I have yet to find a more useful and comprehensive database for all types of drugs.

William C. Stafford Fulgurite AB

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Frequently asked questions

Cortellis Drug Discovery Intelligence is trusted by researchers across biopharma and academia, including R&D executives, biologists, pharmacologists, DMPK specialists, medicinal chemists, biomarker and translational scientists.

Cortellis Drug Discovery Intelligence provides you with an integrated source of biological, chemical, and pharmacological data from disparate sources into a single drug discovery platform. Our team of scientific experts select and curate data from the following sources:

  • 1500+ scientific journals
  • 160+ international conferences
  • 7 main patent offices
  • Regulatory agencies (FDA, EMA, PMDA & TGA)​
  • ClinicalTrials.gov
  • Pharma & biotech company web pages

Pathway maps are exclusive, curated biological pathways provided in the Cortellis Drug Discovery Intelligence platform. They are graphical representations of molecular and cellular processes that allow you to explore the biological plausibility of the mechanism of action or biomarker of interest by visualizing cellular signaling highlighting key upstream and downstream regulators of a target.

These maps allow you to overlay known drug targets, disease relationships, and adverse events to understand the biological rationale behind a disease or biological process.

Yes, alongside comprehensive insights into animal models used in prior research, this drug discovery platform empowers medicinal chemists and pharmacologists to replace, reduce, and refine the use of animal models for drug testing by confidently assessing organ-on-a-chip and organoid models.

This winning combination provides R&D teams with a holistic approach for optimizing drug discovery and accelerating preclinical testing. By coupling comprehensive biological, chemical and pharmacological data from Cortellis Drug Discovery Intelligence with drug safety data from OFF-X, researchers can anticipate risks and successfully translate drugs from lab to clinic.

Yes, you can leverage bulk data from this drug discovery database as a data feed or API to populate internal data and analytics solutions.

Successfully translate your drug from lab to clinic with Clarivate R&D solutions.

MetaBase & MetaCore

Accelerate drug discovery research

Life Sciences and Healthcare Consulting Services

Improving patient lives by helping clients discover, develop and bring new treatments and devices to market

OFF-X Translational Safety Intelligence

A unique translational tool providing drug and class safety intelligence to anticipate risks and drive new competitive value

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