Product logins

Find logins to all Clarivate products below.


Dry and Wet Age-Related Macular Degeneration | Special Topics | Beovu: Three Months Postlaunch for Wet AMD | US | 2020

Novartis’s Beovu (brolucizumab-dbll) is the fourth vascular endothelial growth factor (VEGF) inhibitor to launch for the treatment of wet age-related macular degeneration (AMD) in the United States and the first  product to launch for this indication since Eylea in 2011. Beovu offers the potential for dosing once every 12 weeks immediately after the first three monthly doses, giving the product a dosing advantage over Lucentis and Eylea in its product labeling. Additionally, Beovu was found to be superior to Eylea in improving some anatomical outcomes in pivotal clinical trials. A competitive price from Novartis, coupled with the possibility of a less-burdensome dosing frequency, will likely ease Beovu’s incorporation into clinical practice. This report provides a snapshot of Beovu’s performance based on physician responses three months after its launch.

QUESTIONS ANSWERED

  • What are the awareness of, familiarity with, and perceptions related to Beovu among U.S. ophthalmologists / retinal specialists three months after launch?
  • Is Beovu being prescribed to treatment-naive patients or as a switch therapy? What are the reasons for prescribing Beovu for wet AMD, and how satisfied are prescribers with the product?
  • What are the main obstacles holding physicians back from administering Beovu to more of their wet AMD patients? Why have some physicians not yet used Beovu for wet AMD?
  • What promotional messages and activities is Novartis using to support Beovu’s launch for wet AMD?

CONTENT HIGHLIGHTS

Geography: United States

Primary Research: Survey of 75 U.S. ophthalmologists / retinal specialists in January 2020

Key metrics included: Unaided and aided awareness of Beovu; familiarity with and impressions of Beovu; prescriber and nonprescriber profiles; willingness to prescribe Beovu; performance of Beovu on key attributes; sales representative visit frequency, reach, and effectiveness; benchmarking against Eylea

PRODUCT DESCRIPTION

DRG’s Special Topics reports assess key trends in dynamic disease areas. Here we provide a snapshot of Beovu’s performance at three months postlaunch in the U.S. wet AMD market. Specifically, we assess U.S. physicians’ awareness, perceptions, and usage of Beovu, as well as its current and future impact on competitor therapies and the overall market. Insight is also provided on promotional efforts by Novartis, prescriber and nonprescriber profiles, and benchmarking against Eylea three months after it launched for wet AMD.

Related Market Assessment Reports

Report
Psoriatic Arthritis – Current Treatment – Treatment Algorithms: Claims Data Analysis – Psoriatic Arthritis (US)
Treatment of psoriatic arthritis (PsA) typically begins with conventional DMARDs, such as methotrexate, and progresses to more-potent biologics and/or targeted oral therapies as needed. The U.S…
Report
Atopic Dermatitis / Atopic Eczema – Access & Reimbursement – Access & Reimbursement – Atopic Dermatitis (US)
The treatment landscape for AD in the United States is evolving rapidly. Since 2017, the FDA has approved multiple agents, including systemic and topical JAK inhibitors, nonsteroidal topical…
Report
Renal Anemia – Current Treatment – Treatment Algorithms: Claims Data Analysis – Renal Anemia (US)
Renal anemia is a common complication of chronic kidney disease (CKD). When kidneys are diseased or impaired, they fail to generate enough EPO, causing renal anemia. The primary goal of renal…
Report
Painful Diabetic Neuropathy – Current Treatment – Treatment Algorithms: Claims Data Analysis – Painful Diabetic Neuropathy (US)
Painful diabetic neuropathy (PDN) is characterized by numbness, tingling, and burning, sharp, shooting, or other painful sensations, commonly in the feet, legs, and/or hands. PDN is managed with…
Report
Systemic Lupus Erythematosus – Landscape & Forecast – Disease Landscape & Forecast (G7)
Systemic lupus erythematosus (SLE) is a complex autoimmune disease that can affect nearly any organ or system in the body. As a result, its course, manifestations, and treatment can be highly…