Product logins

Find logins to all Clarivate products below.


Myelodysplastic Syndromes | Niche & Rare Disease Landscape & Forecast | US/EU5 | 2024

Myelodysplastic syndromes (MDS) are a heterogeneous collection of hematopoietic stem cell disorders that result in cytopenia and the risk of progression to acute myeloid leukemia (AML). Bristol Myers Squibb / Acceleron’s Reblozyl (luspatercept) for lower-risk adult MDS, Astex Pharmaceuticals’ Inqovi (decitabine and cedazuridine) for higher-risk adult MDS and refractory MDS, Geron Corporation’s Rytelo (imetelstat) for low- to intermediate-1-risk MDS with transfusion-dependent anemia, and Servier’s Tibsovo (ivosidenib) for relapsed or refractory MDS with an IDH1 mutation are effective treatments. Other pharmacological approaches to managing the disease (e.g., growth factor stimulants [e.g., erythropoietin-stimulating agents], lenalidomide [Revlimid, generics], hypomethylating agents [e.g., azacitidine]) are designed to ameliorate the symptoms and extend patients’ survival, although there is a significant gap in the treatment of refractory disease. The MDS pipeline is robust, and several projected market entrants are poised to penetrate both lower- and higher-risk subpopulations.

Questions answered

  • How will the launches of Reblozyl (luspatercept), Inqovi (decitabine and cedazuridine), Rytelo (imetelstat), and Tibsovo (ivosidenib) change MDS treatment?
  • What is the commercial outlook for current and emerging therapies for MDS?
  • Which emerging therapies are most likely to have an impact on the MDS therapy market by 2033?
  • How will the size of the MDS population change by 2033?

Geography: United States and EU5

Primary research: Six country-specific interviews with thought-leading hematologists supported by survey data collected for this study

Epidemiology: Diagnosed incident and diagnosed prevalent cases of MDS by country, drug-treated prevalent and incident cases of MDS, diagnosed incident and prevalent cases of MDS by morphology, and diagnosed prevalent cases by prognostic risk

Forecast: Drug-level sales and patient share of key MDS therapies through 2033

Drug treatments: Coverage of key current and emerging therapies

Product description

Niche & Rare Disease Landscape & Forecast provides comprehensive market intelligence with world-class epidemiology, keen insight into current and emerging therapies, and drug forecasts supported by detailed primary and secondary research.

Key feature

Niche & Rare Disease Landscape & Forecast features a Drug Pipeline chapter with real-time, global pipeline intelligence content directly from Cortellis. This chapter is updated daily and features interactive figures that can be easily downloaded for detailed analysis or presentations.

Related Market Assessment Reports

Report
Eosinophilic Esophagitis – Current Treatment – Treatment Algorithms: Claims Data Analysis – Eosinophilic Esophagitis (US)
Eosinophilic esophagitis (EoE) is a chronic allergic inflammatory condition of the esophagus, marked by an accumulation of eosinophils. This can lead to difficulty swallowing and potentially…
Report
Metabolic Dysfunction-Associated Steatohepatitis – Unmet Need – Unmet Need – Metabolic Dysfunction-Associated Steatohepatitis (US/EU)
Metabolic dysfunction-associated steatohepatitis (MASH), previously known as nonalcoholic steatohepatitis (NASH), has the potential to be a large and lucrative therapy market owing to the disease…
Report
Human Immunodeficiency Virus – Landscape & Forecast – Disease Landscape & Forecast (G7)
The HIV therapy market is undergoing significant transformation, driven by innovative ARVs and evolving treatment strategies. The market is crowded with many approved ARVs, including STRs such as…
Report
Multiple Myeloma – Geographic Focus: China – Multiple Myeloma – China In-Depth (China)
China’s multiple myeloma therapy market is evolving rapidly, driven by an increasing disease burden and advances in treatment options. Current therapies in China largely mirror global standards;…
Report
Hepatocellular Carcinoma – Geographic Focus: China – Hepatocellular Carcinoma – China In-Depth (China)
The hepatocellular carcinoma therapy market in China is poised to experience significant growth, driven by an aging population and the high prevalence of hepatitis B and C infection. Angiogenesis…