Ulcerative Colitis – Landscape & Forecast – Disease Landscape & Forecast (G7)

We expect the ulcerative colitis (UC) therapy market to grow steadily over the next decade, primarily driven by the increasing use of non-tumor necrosis factor (TNF) biologics (e.g., Takeda’s Entyvio, Johnson & Johnson Innovative Medicine’s Stelara, AbbVie’s Rinvoq) earlier in the treatment algorithm. Additionally, the availability of Pfizer’s Xeljanz / Xeljanz XR, BMS’s Zeposia, and Alfasigma’s Jyseleca has expanded the treatment armamentarium and intensified market competition. Furthermore, the recent approvals of Pfizer’s Velsipity, Eli Lilly’s Omvoh, AbbVie’s Skyrizi, Johnson & Johnson Innovative Medicine’s Tremfya, and the expected launch of several therapies with novel mechanisms of action (e.g., ABX464, ivarmacitinib, MK-7240) will drive market growth over the next decade. Offsetting this growth will be the continued generic erosion of conventional agents, along with the entry of and increased physician comfort prescribing less-expensive biosimilars.

QUESTIONS ANSWERED

• What are the similarities and differences in how U.S., European, and Japanese gastroenterologists treat UC?
• How do gastroenterologists perceive biosimilar agents, and what has been / will be their impact on the UC market?
• What are key opinion leaders’ (KOLs’) insights into the current treatment options for TNF-refractory UC (e.g., Xeljanz / Xeljanz XR, Entyvio, Stelara, Rinvoq, Zeposia, Jyseleca)? What factors drive their treatment decisions?
• What are KOLs’ perceptions of recently approved / key emerging therapies (e.g., Skyrizi, Tremfya, Velsipity, Omvoh), and where do they see these agents fitting into the treatment algorithm?
• How will the market evolve over the next 10 years?

CONTENT HIGHLIGHTS

Geographies: United States, France, Germany, Italy, Spain, United Kingdom, Japan.

Primary research: 26 country-specific interviews with thought-leading gastroenterologists supported by survey data collected for this and other Clarivate research.

Epidemiology: Diagnosed prevalence of UC by country, segmented by disease activity.

Forecast: 10-year, annualized, drug-level sales and patient share of key UC therapies through 2033, segmented by brands / generics / biosimilars, and acute and maintenance settings.

Drug treatments: Coverage of key current and emerging therapies

PRODUCT DESCRIPTION

Disease Landscape & Forecast provides comprehensive market intelligence with world-class epidemiology, keen insight into current and emerging therapies, and drug forecasts supported by detailed primary and secondary research.

SOLUTION ENHANCEMENT