Atrial Fibrillation | Disease Landscape & Forecast | G7 | 2023
Atrial fibrillation (AF) is an abnormal heart rhythm characterized by rapid and irregular beats of the atrial chambers of the heart. AF is the most common arrhythmia treated in clinical practice. Pharmacological treatment includes rate control therapy (e.g., beta blockers, calcium channel blockers, digoxin) and anticoagulation therapy (e.g., vitamin K antagonists, direct-acting oral anticoagulants [DOACs]). Novel agents being investigated in clinical trials to treat AF include Anthos Therapeutics’ abelacimab, Bayer’s asundexian, Janssen’s milvexian, and ARCA’s bucindolol. We expect some of these drugs to launch during our forecast period and fulfill some of the unmet needs that remain in AF. Unmet needs include superior efficacy and safety / tolerability of antiarrythmic drugs, as bradycardia is an important safety concern in AF patients, and superior safety of anticoagulant drugs for stroke prevention in AF.
Questions answered
- What do key opinion leaders think about emerging therapies such as Anthos Therapeutics’ abelacimab, Bayer’s asundexian, Janssen’s milvexian, and ARCA’s bucindolol? How will emerging therapies differentiate themselves in an increasingly crowded market?
- What are the key treatment drivers and goals within AF? How do current therapies perform on these goals?
- What are the key unmet needs in AF, and how likely are they to be met?
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Disease Landscape & Forecast provides comprehensive market intelligence with world-class epidemiology, keen insight into current treatment paradigms, in-depth pipeline assessments, and drug forecasts supported by detailed primary and secondary research.
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