Product logins

Find logins to all Clarivate products below.


Non-Small-Cell Lung Cancer | Current Treatment: Physician Insights | US | May 2025

Immune checkpoint inhibitors continue to dominate the treatment of non-small-cell lung cancer (NSCLC), while biomarker-based approaches are driving increasing patient segmentation. In 2024, Imfinzi and Alecensa gained label expansions into the resectable early-stage NSCLC space. Additionally, Opdivo plus chemotherapy gained FDA approval for perioperative (neoadjuvant then adjuvant) use in this setting. The metastatic setting also saw new entrants to the space, with the approval of new biomarker-targeted agents: Bizengri for NRG1-mutated NSCLC, and Ensacove for NSCLC with ALK mutations. Additionally, Tecentriq Hybreza, a subcutaneous formulation of Tecentriq, was also approved in all adult indications approved for Tecentriq, including NSCLC. These approvals, against the backdrop of numerous existing agents in the NSCLC space, provide medical oncologists with an ever-increasing array of treatment options.

Questions answered

  • What are the treatment rates for NSCLC in the various settings and lines of therapy?
  • What are the rates of testing for different biomarkers, and what is the uptake of key biomarker-driven therapies?
  • How are new therapy entrants to the NSCLC market performing relative to existing therapies?
  • What do surveyed physicians consider the main drivers of and key obstacles to the uptake of select therapies?

Product description

Through survey data from U.S. physicians, Current Treatment: Physician Insights offers in-depth analyses of the reasons behind treatment dynamics, prescribing behavior, and brand preference, enabling you to:

  • Understand the treatment landscape for a disease and how physicians make prescribing decisions.
  • Evaluate the drivers and obstacles that influence treatment selection.
  • Analyze your brand’s performance from the physician perspective to enhance or defend your competitive position.

Primary research: Survey of 102 U.S. medical oncologists in the United States fielded during February 24 to March 7, 2025.

Key drugs covered: Alecensa, Enhertu, Gavreto, Imfinzi, Imjudo, Keytruda, Krazati, Libtayo, Lumakras, Opdivo, Retevmo, Rybrevant, Tabrecta, Tagrisso, Tecentriq, Tecentriq Hybreza, Tepmetko, Yervoy.

Related Market Assessment Reports

Report
Non-Small-Cell Lung Cancer – Landscape & Forecast – Disease Landscape & Forecast (G7)
The multibillion-dollar NSCLC therapy market is highly dynamic, with a plethora of approved therapies but still a high unmet need. Immune checkpoint inhibitors such as Keytruda (Merck & Co.)…
Report
Major Depressive Disorder (DSM-V) – Current Treatment – Current Treatment: Physician Insights – Major Depressive Disorder (EU5)
Across the EU5, the treatment landscape for major depressive disorder (MDD) is shaped by the widespread use of SSRIs and SNRIs, which continue to serve as firstline therapy due to their…
Report
Non-Small-Cell Lung Cancer – Unmet Need – Unmet Need – Metastatic NSCLC without driver mutations (US EU)
First-line treatment for non-small-cell lung cancer (NSCLC) patients without driver mutations typically includes an immune checkpoint inhibitor, with or without platinum-based chemotherapy,…
Report
Psoriasis – Unmet Need – Unmet Need – Moderate to Severe Psoriasis (US/EU)
Topical therapies are the backbone of psoriasis management; however, they are often inadequate for patients with moderate to severe disease, who typically require systemic treatment. While…
Report
Eosinophilic Esophagitis – Unmet Need – Unmet Need – Eosinophilic Esophagitis (US/EU)
Standard treatments for eosinophilic esophagitis (EoE) typically include proton pump inhibitors (PPIs) and swallowed topical steroids. Although these therapies can alleviate EoE symptoms, their…