Immune Thrombocytopenic Purpura | Treatment Algorithms: Claims Data Analysis | US | 2024

Immune thrombocytopenic purpura (ITP) is an autoimmune disorder that leads to a decline in platelet production, thus increasing the risk of bleeding. Current therapies for ITP can be broadly divided into immunomodulators, thrombopoietin receptor agonists (TPO-RAs), and spleen tyrosine kinase inhibitors (Syk inhibitors). Systemic glucocorticoids and TPO-RAs are the cornerstones of clinical management; however, the Syk inhibitor fostamatinib (Rigel Pharmaceuticals’ Tavalisse) and biologics such as rituximab provide additional options for refractory disease. This report offers insights from real-world claims data into prescribing trends for ITP to help new players better understand current treatment practices that may define the market niche for their emerging product.

Questions answered

• What shares do key therapies and brands garner by line of therapy in newly diagnosed ITP patients? What are the quarterly trends in prescribing among recently treated and newly diagnosed ITP patients?
• How have TPO-RAs and fostamatinib been integrated into the treatment algorithm, and what are their sources of business?
• What percentage of ITP patients receive drug therapy within one year of diagnosis, and how quickly? What percentage of patients progress to later lines of therapy within one year of diagnosis?
• What percentage of ITP patients are treated with monotherapy vs. combination therapy? What are the most commonly used combinations?
• What are the product-level compliance and persistency rates among drug-treated patients?

Product description

Treatment Algorithms: Claims Data Analysis provides detailed, quantitative analysis of the treatment journey and brand usage across lines of therapy and overall using real-world, patient-level claims data so that marketers can accurately assess their source of business, benchmark usage against competitors, and quantify areas of opportunity for their marketed or emerging brand.

Markets covered: United States

Key companies: Amgen, Novartis, Rigel Pharmaceuticals, Sobi

Key drugs: Antibiotics, avatrombopag (Doptelet), eltrombopag (Promacta), fostamatinib (Tavalisse), rituximab (Rituxan, biosimilars), romiplostim (Nplate), systemic glucocorticoids

Key features

Dashboard featuring interactive visuals, easy navigation, and expanded analyses.